Active substanceNitrofuralNitrofural
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  • Dosage form: & nbsptablets for solution for local and external use
    Composition:

    Active substance: furatsilin - 20.0 mg;

    Excipients: sodium chloride - 800.0 mg.
    Description:

    Tablets are round, flat, with a facet and a risk on one side,yellow or greenish-yellow color with uneven surface color.

    Pharmacotherapeutic group:Antimicrobial agent - nitrofuran
    ATX: & nbsp

    D.08.A.F.01   Nitrofural

    Pharmacodynamics:

    Furacilin is an antimicrobial agent derived from nitrofuran. Microbial flavoproteins, restoring the 5-nitro group, form highly reactive amino derivatives, capable of causing conformational changes in proteins (including ribosomal) and other macromolecules, leading to the death of bacteria.

    It is active against gram-positive and gram-negative bacteria: Staphylococcus spp, Streptococcus spp, Escherichia coli, Clostridium perfringens.

    Sustainability develops slowly and does not reach a high degree.

    Pharmacokinetics:

    With external and local application, the absorption is insignificant. It penetrates through the histogematic barriers and is evenly distributed in liquids and tissues. The main pathway of metabolism is the reduction of the nitro group. It is excreted by the kidneys and partly with bile.

    Indications:

    Outwardly: purulent wounds, pressure sores, burns II-III st, small skin lesions (including abrasions, scratches, cracks, cuts).

    Locally: blepharitis, conjunctivitis, osteomyelitis, empyema of the paranasal sinuses, pleura, urinary tract infections - rinsing of the cavities, acute tonsillitis, stomatitis, gingivitis.

    If necessary, please consult with your doctor before using the medication.

    Contraindications:

    Hypersensitivity to nitrofural, nitrofuran derivatives and / or other components of the composition, bleeding, allergic dermatoses, marked renal impairment.

    Pregnancy and lactation:

    Application in pregnancy and during breastfeeding is possible if the intended benefit to the mother exceeds the potential risk to the fetus or child.

    Dosing and Administration:

    Locally, externally.

    Adults, an aqueous 0.02% solution of nitrofural is prepared immediately before use: one tablet (20 mg of furacilin) ​​is dissolved in 100 ml of distilled water at room temperature or in warm boiled water. For faster dissolution, boiling or hot water. The solution is then cooled to room temperature.

    Outwardly, in the form of an aqueous 0,02% solution - water the wounds and impose moist bandages.

    Locally: empyema of the paranasal sinuses (including with sinusitis) - rinsing of the cavity; osteomyelitis after the operation - rinsing the cavity with the subsequent application of a moist bandage; pleural empyema - after removal of pus, the pleural cavity is flushed and 20-100 ml of an aqueous solution is injected.To wash the urethra and bladder, an aqueous solution with an exposure of 20 minutes is used.

    With blepharitis, conjunctivitis is instillation of 0.02% solution into the conjunctival sac.

    In acute tonsillitis, stomatitis, gingivitis - mouth and throat rinsing with a warm 0.02% solution of 100 ml 2-3 times a day.

    Duration of treatment - according to the indications depending on the nature and localization of the affected area.

    Use the drug only according to the method of administration and the doses specified in the instructions.

    If necessary, please consult with your doctor before using the medication.

    Side effects:

    Allergic reactions, dermatitis, skin itching.

    If any of the side effects indicated in the manual are aggravated, or any other side effects not indicated in the instructions are noted, you should inform the doctor immediately.

    Overdose:

    No cases of overdose have been reported.

    Interaction:

    Not identified.

    Special instructions:Not studied.
    Effect on the ability to drive transp. cf. and fur:

    The drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities,requiring increased concentration of attention and speed of psychomotor reactions.

    Form release / dosage:

    Tablets for solution for local and external use, 20 mg.

    Packaging:

    For 10 tablets in a contour mesh box made of polyvinylchloride film and aluminum foil printed lacquered.

    1 the contoured cell pack together with the instruction for use is placed in a pack of cardboard.

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 of the year.

    Do not use after the expiry date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-004017
    Date of registration:12.12.2016
    Expiration Date:12.12.2021
    The owner of the registration certificate:FORP, CJSCFORP, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp19.01.2017
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