Geksoral - instructions for use, dose, side effects, contraindications

Excipients: ethanol 96% - 4.3333 g, polysorbate 60 - 0.7 g, peppermint oil 0.064 g, anise oil 0.0339 g, citric acid, monohydrate 0.0418 g, sodium saccharin 0.022 g, levometrogol - 0.0186 g, methyl salicylate 0.0186 g, clove oil 0.0084 g, eucalyptus oil 0.0011 g, azorubin 85% (E 122) 0.0023 g, purified water 100 ml.

Description:Transparent liquid of red color with a smell of mint.

Pharmacotherapeutic group:Antiseptic

ATX: & nbsp

A.01.A.B.12 Hexetidine

Pharmacodynamics:

The antimicrobial effect of the drug "Hexorol®" is associated with the suppression of oxidative reactions of the metabolism of bacteria (thiamine antagonist). The drug has a broad spectrum of antibacterial and antifungal effects, in particular against gram-positive bacteria and fungi of the genus Candida, however, the drug "Hexoral®" can also have an effect in the treatment of infections caused, for example, by Pseudomonas aeruginosa or Proteus spp.At a concentration of 100 mg / ml, the drug suppresses most strains of bacteria. The development of stability was not observed. Hexetidine has a weak anesthetic effect on the mucosa.

The drug has an antiviral effect against influenza A viruses, respiratory syncytial virus (PC virus), herpes simplex virus type 1, affecting the respiratory tract.

Pharmacokinetics:

Hexetidine adheres very well on the mucous membrane and is not practically absorbed.

After a single application of the active substance, its traces are found on the gingival mucosa for 65 hours. In dental plaque, active concentrations persist for 10-14 hours after application.

Indications:

As a symptomatic agent.

- Symptomatic treatment for inflammatory-infectious diseases of the oral cavity and larynx:

- tonsillitis, tonsillitis (including Plaut-Vincent's angina, angina of lateral ridges), pharyngitis, gingivitis, stomatitis, glossitis, periodontitis;

- fungal diseases;

- prevention of infectious complications before and after surgical interventions in the oral cavity and larynx and in trauma, including prevention of infection of the alveoli after extraction of the tooth;

- hygiene of the oral cavity, including and to eliminate bad breath from the mouth.

Contraindications:

- Hypersensitivity to any of the components of the drug;

- erosive-desquamous lesions of the mucous membrane of the oral cavity;

- Children under 3 years old.

Carefully:With increased sensitivity to acetylsalicylic acid.

Pregnancy and lactation:Information about any undesirable effects of the drug "Hexoral ®" during pregnancy and during breastfeeding there. However, before prescribing Hexorol® to pregnant or lactating women, the physician should carefully weigh the benefits and risks of treatment, given the lack of sufficient data on the penetration of the drug through the placenta and into breast milk.

Dosing and Administration:

Locally. Children from 3 to 6 years: use of the drug is possible after consultation with a medical professional. Children can use the drug from such an age when there is no danger of uncontrolled swallowing when applying the solution.

Adults and children over 6 years of age: Fill the measuring cup to 15 ml mark and rinse the mouth and larynx 15 ml of undiluted solution for at least 30 seconds 2-3 times a day.

Hexetidip adheres to the mucosa and thus gives a lasting effect. In this regard, the drug should be used after meals.

The drug "Hexoral®", the topical solution can only be used to rinse the mouth and larynx. Do not swallow the solution.

Always use undiluted solution.

In the treatment of diseases of the oral cavity the drug can also be applied with a tampon for 2-3 minutes. The duration of treatment is determined by the doctor.

Side effects:

Undesirable reactions identified by post-marketing use of the drug were classified as follows: very frequent (≥ 1/10), frequent (≥ 1/100, <1/10), not frequent (≥ 1/1000, <1/100), rare (≥ 1/10000, <1/1000), very rare (<1/10000), the frequency is unknown (the incidence rate can not be estimated from the available data).

Impaired immune system. Very rarely: hypersensitivity reactions (including urticaria), angioedema.

Violations from the nervous system. Very rarely: agesia, dysgeusia.

Disturbances from the respiratory system, chest and mediastinum.

Very rarely: cough, shortness of breath due to the appearance of a hypersensitivity reaction.

Disturbances from the gastrointestinal tract. Very rarely: dry mouth, dysphagia, nausea, enlarged salivary glands, vomiting.

General disorders and disorders at the site of administration. Very rarely: reactions at the site of application (including irritation of the mucous membrane of the mouth and throat, burning sensation, oral paresthesia, discoloration of the tongue, discoloration of the teeth, inflammation, blistering and ulceration).

If any of the side effects indicated in the instructions are aggravated or you notice other side effects, it is recommended that you consult a doctor.

Overdose:

It is unlikely that hexethidine can have toxic effects when applied according to the instructions for use of the drug. Ingestion of large quantities of the preparation containing ethanol, can lead to the appearance of signs / symptoms of alcohol intoxication.

In all cases of overdose, consult a doctor immediately. Treatment is symptomatic, as with alcohol intoxication. Gastric lavage is necessary within 2 hours after ingestion of an excessive dose.

Interaction:No data available.

Special instructions:

Medicinal preparation "Geksoral®", a topical solution can be used to rinse the mouth and throat only if the patient can spit out the raster after rinsing." Hexoral®", the topical solution contains ethanol 96% (4.3333 g / 100 ml solution).

If the medicine has become unusable or the expiration date has expired, do not throw it into the waste water and throw it out! Place the drug in a bag and put it in the trash. These measures will help protect the environment!

Effect on the ability to drive transp. cf. and fur:The medicinal preparation "Hexorol®", aerosol for topical application does not affect the ability to drive vehicles and engage in other potentially hazardous activities.

Form release / dosage:Topical solution 0.1%.

Packaging:

For 200 ml of the drug in a vial of colorless glass (III type) with an aluminum screw cap with the control of the first opening.

One bottle together with a measuring cup and instructions for use in a cardboard bundle.

Storage conditions:

Store at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use the product after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:П N014010 / 02

Date of registration:06.08.2010 / 24.07.2015

Expiration Date:Unlimited

The owner of the registration certificate:Johnson & Johnson, LLC Johnson & Johnson, LLC Russia

Manufacturer: & nbsp

FAMAR ORLEANS France

Representation: & nbspJohnson & Johnson LLC Johnson & Johnson LLC Russia

Information update date: & nbsp20.03.2017

Illustrated instructions

Instructions

Hexoral® (Hexoral®)