Active substanceHexetidineHexetidine Similar drugsTo uncover Hexoral® aerosol locally Johnson & Johnson, LLC Russia Hexoral® solution locally Johnson & Johnson, LLC Russia Hexetidine spray locally YUZHFARM, LLC Russia Maxcold® Lor spray locally Otisipharm, PAO Stomatidin® solution locally Boznalek, AO Bosnia and Herzegovina Stopangin® spray locally Teva Pharmaceutical Enterprises Co., Ltd. Israel Stopangin® solution locally Teva Pharmaceutical Enterprises Co., Ltd. Israel Dosage form: & nbsptopical solution Composition:1 ml of the solution contains:Active substance - hexiethidine 1.00 mgExcipients:propylene glycol 100.00 mg, polysorbate-20 10.00 mg, citric acid monohydrate 0.40 mg, sodium saccharinate 0.30 mg, racemenol 0.15 mg, methyl salicylate 0.10 mg, dye azorubin 0.10 mg, ethanol 96 % 0.10 ml, water to 1.00 ml. Description:Transparent liquid is red. Pharmacotherapeutic group:antiseptic ATX: & nbspA.01.A.B.12 Hexetidine Pharmacodynamics:Antiseptic drug for topical application in otorhinolaryngology and dentistry.The antimicrobial effect of hexiethidine is associated with the suppression of oxidative reactions of the metabolism of microbial cells (antagonist, thiamine). The drug has antibacterial action against gram-negative and gram-positive bacteria, Pseudomonas aeruginosa and Proteus spp.and antifungal action (including against fungi of the genus Candida). At a concentration of 100 mg / ml, the growth of most strains of bacteria is suppressed. Development of stability was not observed. Hexetidine has a weak analgesic effect on the mucous membrane. Pharmacokinetics:Hexetidine well adheres to the mucosa and is not practically absorbed. After a single application hexethidine is found on the oral mucosa for 65 hours. In dental plaques, active concentrations persist for 10-14 hours after application. Indications:Inflammatory and infectious diseases of the oral cavity and pharynx: angina (including angina with defeat of lateral ridges, Plaut-Vincent's angina), pharyngitis, gingivitis and bleeding gums, periodontitis, stomatitis, glossitis, aphthous ulcers with the goal of preventing superinfection, infection alveolus after tooth extraction, fungal infections of the oral cavity and pharynx, especially candidal stomatitis, before and after operations in the oral cavity and pharynx, additional oral hygiene in common diseases, elimination of bad breath, especially in the case of collapsing tumors of the oral cavity and pharynx. Contraindications:Children under 5 years.Hypersensitivity to any of the components of the drug. Hypersensitivity, atrophic pharyngitis, pregnancy (I trimester). Pregnancy and lactation:There is insufficient data on the penetration of hexadetidine through the placenta and into breast milk. It is possible to use the drug during pregnancy, if the potential benefit to the mother exceeds the risk to the fetus. If it is necessary to use the drug during lactation, it is necessary to solve the problem of stopping breastfeeding. Dosing and Administration:Locally.For rinsing, always use undiluted drug.The solution must not be swallowed. It is necessary to spit out the solution after rinsing.For oral diseases in adults and children over the age of 5 years, rinse the mouth with 10-15 ml (one tablespoon) of undiluted drug solution for 30 seconds. For throat diseases in adults and children over the age of 5 years, rinse with the same amount of undiluted drug solution for 30 seconds. When treating diseases of the oral cavity, the drug can be applied with a tampon.Apply 2 times a day (preferably in the morning and in the evening), after eating. Duration of the drug is determined individually. If the symptoms do not disappear after 5 days of use and / or accompanied by fever, you should consult your doctor. Side effects:Burning, irritation and mild dryness of the oral mucosa, allergic reactions. With prolonged use, it is possible to change the taste sensations. After discontinuation of the drug side effects disappear. Overdose:If you accidentally swallow large amounts of the drug, you may experience nausea and vomiting!In case of an overdose, it is necessary to wash the stomach and prescribe symptomatic therapy. Interaction:Not described. Special instructions:Do not use the drug in the category of patients who can not independently carry out this procedure (rinsing). Effect on the ability to drive transp. cf. and fur:The drug does not affect the ability to drive vehicles or work with mechanisms.The preparation contains 10% ethanol (ethyl alcohol 96%).The drug should be taken no later than 30 minutes before the start of driving. Form release / dosage:Topical solution 0.1%. Packaging:For 200 ml in a bottle of dark glass, sealed with an aluminum lid with a control of the first opening, or a screw-on plastic lid, equipped with a child protection mechanism, sealant and control of the first opening. One bottle with instructions for use is placed in a cardboard box. Storage conditions:At a temperature of no higher than 25 ° C. Do not freeze. Keep out of the reach of children! Shelf life:2 years. Do not use after expiry date. Shelf life after opening the bottle is 6 months. Terms of leave from pharmacies:Without recipe Registration number:П N015357 / 01 Date of registration:12.12.2008 The owner of the registration certificate:Boznalek, AOBoznalek, AO Bosnia and Herzegovina Manufacturer: & nbspBOSNALIJEK, d.d. Bosnia and Herzegovina Representation: & nbspBOSNALEK AO BOSNALEK AO Bosnia and Herzegovina Information update date: & nbsp2015-12-08 Illustrated instructions × Illustrated instructions Instructions