Active substanceHexetidineHexetidine
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  • Dosage form: & nbspspray for topical application
    Composition:

    Composition per 100 ml:

    Active substance: hexiethidine (in terms of 100% substance) - 200 mg (0.2%).

    Excipients: sodium saccharinate dihydrate 40 mg, citric acid monohydrate 70 mg, sodium hydroxide (sodium hydroxide) 19 mg, glycerol 17,000 mg, ethanol (rectified ethyl alcohol) 4000 mg, lauro macrogol (macrogol lauryl ether) -1500 mg, cineole (eucalyptol) 20 mg, levomentol (L-Menthol) 20 mg, peppermint mint oil 10 mg, purified water 100.0 ml.

    Description:Almost colorless liquid with a characteristic smell of menthol, located in an aluminum cylinder with a metering pump, equipped with a spray gun for oral use with a protective cap.
    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    A.01.A.B.12   Hexetidine

    Pharmacodynamics:

    Antiseptic agent for topical application for application to mucous membranes.Has antimicrobial, antifungal, analgesic, enveloping and deodorizing action. The antimicrobial effect of Maxocold® Lor is associated with the suppression of oxidative reactions of bacterial metabolismhexethidine thiamine antagonist). The drug has a broad spectrum of antibacterial and antifungal effects, in particular against Gram-positive bacteria and fungi of the genus Candida, however Maxycold® Lor can also have an effect in the treatment of infections caused, for example, by Pseudomonas aeruginosa or Proteus. At a concentration of 100 mg / ml, the drug suppresses most strains of bacteria. The development of stability was not observed. Maxicold® Lor has a weak anesthetic effect on the mucous membrane.

    The drug has an antiviral effect against influenza A viruses, respiratory syncytial virus (PC virus), herpes simplex virus type 1, affecting the respiratory tract.

    Pharmacokinetics:

    After a single use, the local action of hexiethidine lasts 10-12 hours. The drug is almost not absorbed from the surface of the mucous membranes and does not have a systemic effect.

    After a single application of the active substance, its traces are found on the gingival mucosa for 65 hours. In dental plaques, active concentrations persist for 10-14 hours after application.

    Indications:

    Infectious and inflammatory diseases of the oral cavity and pharynx (tonsillitis, including Plaut-Vincent's angina, pharyngitis, stomatitis, aphthous ulcers of the oral cavity, glossitis, periodontitis, gingivitis, periodontitis, periodontitis, alveolitis), gum bleeding. With ARI - as an auxiliary, as part of complex therapy.

    Fungal infections of the oral cavity, pharynx and larynx (thrush).

    Injuries and surgical interventions in the oral cavity, pharynx and larynx (both before and after their holding), incl. prevention of infection of the alveoli after extraction of the tooth.

    As a means of hygiene of the oral cavity to eliminate unpleasant odor (deodorizing effect).

    Prevention of superinfections in decaying tumors of the oral cavity and larynx.

    Contraindications:Hypersensitivity, atrophic pharyngitis, children under 3 years.
    Pregnancy and lactation:There is no information about any adverse effects of hexaetidine in pregnancy and lactation.Before prescribing the drug to pregnant or lactating women, the physician should carefully weigh the benefits of treatment for the mother and the possible risk to the fetus and the baby, given the lack of sufficient data on the penetration of the drug through the placenta and into breast milk.
    Dosing and Administration:

    Locally.

    Adults and children over 6 years of age: treated affected areas with a delay in breathing 2 times a day.

    Children from 3 to 6 years: use of the drug is possible after consultation with a medical professional.

    Hexetidine adheres to the mucosa and thus gives a lasting effect. In this regard, the drug should be used after meals.

    General recommendations for the introduction.

    The drug is sprayed into the mouth or throat. With the help of a spray, you can easily and quickly treat affected areas. It is necessary to perform the following actions:

    1. Remove the lid from the cylinder, install the nebulizer in the corresponding opening of the top of the cylinder.

    2. At first use, several short presses on the spray gun (in order to ensure a uniform spraying of the contents of the balloon) must be made beforehand.

    3.Enter the required amount of the drug into the oral cavity by pressing the sprayer 3-4 times until it stops. During the introduction of the drug should hold your breath.

    4. After use, remove the nebulizer, rinse it in running water and dry it at room temperature in a place inaccessible to children.

    5. Store the nebulizer in the package with the product.

    During the introduction, the balloon should be held vertically (see picture)!

    The course of treatment is 5-7 days. If it is necessary to take longer, the duration of treatment is determined by the doctor.

    Side effects:

    Allergic reactions; burning of the oral mucosa; if swallowed accidentally - nausea; with prolonged use, there may be a violation of taste sensations.

    If any of the side effects listed in the manual are aggravated, or if you notice other adverse reactions not listed in the instructions, tell your doctor.

    Overdose:

    Hexetidine in this dosage is not toxic. The ingestion of large amounts of the drug leads to vomiting, so no significant absorption is expected.

    There were no cases of ethanol poisoning in case of an overdose.Acute alcohol poisoning is very unlikely, but it is theoretically possible if a large dose of the drug is ingested by a small child. In all cases of overdose, consult a doctor immediately. Treatment is symptomatic: reception of enterosorbents (activated carbon), gastric lavage, abundant drinking. Gastric lavage is necessary within 2 hours after swallowing an excessive dose.

    Interaction:
    At present, there is no information on interactions with other drugs.
    Special instructions:

    Children can use the drug from such an age when they do not resist the foreign object (spray) in the mouth when applying the spray and are able to hold their breath when injecting the drug.

    The spray should not be inhaled; Avoid contact with the eye. After applying the spray, the applicator should be rinsed with warm water. It should be borne in mind that the spray contains ethanol - 24-48 mg in a daily dose. In the absence of a general reaction to. drug taking Potentially hazardous activities requiring special attention and quick reactions (including driving) are not contraindicated.Attention! The cylinder is under pressure. Do not burn, puncture or open, even if the can is empty.

    Effect on the ability to drive transp. cf. and fur:The drug does not adversely affect the driving of motor vehicles and the performance of potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions.
    Form release / dosage:Spray for topical application 0,2%.
    Packaging:

    For 40 ml in aluminum cylinders (with internal protection), equipped with dosing pumps, spray guns for oral use with protective caps.

    Each cylinder, together with a protective cap, a spray for oral use and instructions for use, is placed in a pack of cardboard.

    Storage conditions:

    At a temperature of no higher than 25 ° C. Keep out of the reach of children.

    Do not freeze!

    Shelf life:3 years. Do not use after the expiration date printed on the package.
    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-008791/10
    Date of registration:26.08.2010 / 27.05.2015
    Expiration Date:Unlimited
    The owner of the registration certificate:Otisipharm, PAO Otisipharm, PAO
    Manufacturer: & nbsp
    Information update date: & nbsp29.03.2018
    Illustrated instructions
    Instructions
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