Grammidine children - instructions for use, doses, side effects, contraindications

gramicidin C dihydrochloride - 1.60 mg (in terms of gramicidin C - 1.50 mg); cetylpyridinium chloride monohydrate - 1.05 mg (in terms of cetylpyridinium chloride - 1.00 mg);

Excipients: silicon dioxide colloid - 5,00 mg, talc - 60,00 mg, citric acid monohydrate - 36,00 mg, aspartame - 12,00 mg, raspberry aroma - 3,60 mg, sorbitol - 1055,75 mg, magnesium stearate - 25.00 mg.

Description:Tablets white or almost white, round, biconcave, embossed "GR" on one side and the smell of raspberries. Allowed a slight marbling.

Pharmacotherapeutic group:Antibiotic + antiseptic

ATX: & nbsp

R.02.A Drugs for the treatment of throat diseases

Pharmacodynamics:Combined drug for the symptomatic treatment of infectious and inflammatory diseases of the throat and oral cavity. The composition of the drug includes an antimicrobial agent gramicidin C and antiseptic - cetylpyridinium chloride. The mechanism of action of gramicidin C is associated with an increase in the permeability of the cytoplasmic membrane of the microbial cell, which violates its stability and causes death. Gramicidin C has antibacterial (bactericidal) action against a wide range of gram-positive and gram-negative microorganisms. Cetylpyridinium chloride refers to antiseptic agents, suppresses the growth and multiplication of pathogens of infectious diseases of the oral cavity. The drug has antimicrobial effect, reduces inflammation, softens unpleasant sensations in the throat, facilitates swallowing, with resorption causes hypersalivation, which facilitates the mechanical cleaning of the oral cavity and pharynx from microorganisms.

Indications:Symptomatic treatment of infectious and inflammatory diseases of the oral cavity and throat, accompanied by pain in the throat and in the oral cavity: pharyngitis, tonsillitis, periodontitis, gingivitis, stomatitis.

Contraindications:

-increased sensitivity to the components of the drug;

-phenylketonuria (the drug contains aspartame);

-period of lactation;

-Children under 4 years old.

Pregnancy and lactation:

Pregnant women should consult a doctor before using the drug. The use of the drug is possible if the potential benefit to the mother exceeds the possible risk to the fetus.

For the duration of treatment, breastfeeding should be discontinued.

Dosing and Administration:

Locally. It is used after eating, by resorption in the mouth, without chewing. Immediately after using the drug should refrain from eating food and drink for 1-2 hours.

Dosage for children from 4 to 12 years: 1 tablet 4 times a day. The maximum daily dose is 4 tablets.

Dosage for children over 12 years and adults: 2 tablets (one after another for 20-30 minutes) 4 times a day. The maximum daily dose is 8 tablets. If there is no therapeutic effect, it is recommended to consult a doctor within 7 days of taking the drug.

Side effects:Allergic reactions to the components of the drug, gastrointestinal disorders (nausea, diarrhea) are possible.

Overdose:

Symptoms: taking the drug in doses exceeding the recommended ones, can cause disturbances on the part of the gastrointestinal tract due to changes in the bacterial microflora: nausea, vomiting, diarrhea.

Treatment: should stop taking the drug and see a doctor.

Interaction:At present, no cases of clinically significant interaction with other drugs have been described.

Special instructions:Grammedin® for children should not be taken with open wounds in the mouth, because cetylpyridinium chloride slows healing of wounds.

Effect on the ability to drive transp. cf. and fur:

The drug does not affect the performance of potentially hazardous activities requiring special attention and quick reactions (driving and other vehicles, working with moving mechanisms, dispatcher and operator work, etc.).

Form release / dosage:

Tablets for resorption of 1.5 mg + 1 mg.

Packaging:

6 or 9 tablets per contour cell package or in a contoured package with a perforation made of a polyvinyl chloride film or a polyvinylchloride / polyvinylidene chloride or combined material (polyamide / aluminum / polyvinyl chloride) and aluminum foil.

2 or 4 contour packs of 6 tablets or 2 contour packs of 9 tablets together with instructions for use are placed in a pack of cardboard.

Storage conditions:In the dark place at a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:2 years. Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-002179

Date of registration:13.08.2013 / 06.04.2017

Expiration Date:13.08.2018

Date of cancellation:2018-08-13

The owner of the registration certificate:VALENTA PHARM, PAO VALENTA PHARM, PAO Russia

Manufacturer: & nbsp

VALENTA PHARMACEUTICS, JSC Russia

Information update date: & nbsp07.05.2017

Illustrated instructions

Instructions

Gramdin® for children (Grammidin® for children)