Grammedin neo - instructions for use, dose, side effects, contraindications

gramicidin C dihydrochloride - 3.20 mg (in terms of gramicidin C - 3.00 mg) cetylniridinium chloride monohydrate -1.05 mg (in terms of cetylniridinium chloride - 1.00 mg)

Excipients: silicon dioxide colloid - 5,00 mg, talc - 60,00 mg, acesulfame potassium -15,00 mg, flavoring mint - 25,00 mg, sorbitol - 1065,75 mg, magnesium stearate-25,00 mg.

Description:Tablets of white color round biconcave with an inscription on one side of GR.

Pharmacotherapeutic group:Antibiotic + antiseptic

ATX: & nbsp

R.02.A Drugs for the treatment of throat diseases

Pharmacodynamics:

Combined drug for the treatment of infectious and inflammatory diseases of the throat and oral cavity. The composition of the drug includes an antimicrobial agent gramicidin C and antiseptic - cetylpyridinium chloride.

The mechanism of action of gramicidin C is associated with increased permeability of the cytoplasmic membrane of a microbial cell that gives its resistance and causes destruction of cells. Gramicidin C has a pronounced antimicrobial effect against the causative agents of infectious diseases of the oral cavity and pharynx.

Cetylpyridinium chloride refers to antiseptic agents. Suppresses the growth and reproduction of pathogens infectious diseases of the mouth.

The drug reduces inflammation, has an antimicrobial effect, softens unpleasant sensations in the throat, facilitates swallowing, with resorption causes hypersalivation, which facilitates the mechanical cleaning of the oral cavity and pharynx from microorganisms.

Pharmacokinetics:The drug has a local effect and is practically not absorbed in the gastrointestinal tract, which determines the almost complete absence of systemic effects.

Indications:Infectious and inflammatory diseases of the oral cavity and throat: angina, pharyngitis, tonsillitis, periodontitis, gingivitis, stomatitis.

Contraindications:

- hypersensitivity to the components that make up the drug;

- children under 4 years;

- pregnancy (I trimester).

Pregnancy and lactation:It is not recommended to apply the drug during pregnancy (I) trimester. Breastfeeding at the time of taking the drug should be discontinued.

Dosing and Administration:

It is used after eating, by resorption in the mouth without chewing.

Immediately after using the drug should refrain from eating food and drink for 1-2 hours.

Dosage for adults and children over 12 years: 1 tablet 3-4 times a day. Dosage for children from 4 to 12 years: 1 tablet 1 -2 times a day.

If there is no therapeutic effect, it is recommended to consult a doctor within 7 days of taking the drug.

Side effects:In some cases, allergic reactions to the components of the drug are possible.

Interaction:Grammidine® neo enhances the effects of other antimicrobial agents of local and systemic action.

Form release / dosage:

Lozenges.

Packaging:

6 or 9 tablets per contour cell package or in a contoured package with a perforation made of a polyvinylchloride film or a polyvinyl chloride / polyvinylidene chloride or combined material (polyamide / aluminum / polyvinyl chloride) and aluminum foil.

2, 3 or 4 contour packs of 6 tablets or 2 contour packs of 9 tablets together with instructions for use are placed in a pack of cardboard.

Storage conditions:At a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:2 years. Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-010598/08

Date of registration:25.12.2008 / 28.02.2017

Expiration Date:Unlimited

The owner of the registration certificate:VALENTA PHARM, PAO VALENTA PHARM, PAO Russia

Manufacturer: & nbsp

VALENTA PHARMACEUTICS, JSC Russia

Information update date: & nbsp07.05.2017

Illustrated instructions

Instructions

Gramidine® neo (Grammidin® neo)