Idrinol® (Idrinol®)

Meldonium - an analog of gamma-butyrobetaine, inhibits gamma butirobetaingidroksinazu, reduces the synthesis of carnitine and transportation of long chain fatty acids across cell membranes and prevents the accumulation of cells in the activated forms of unoxidized fatty acids - acylcarnitine derivatives and atsilkoenzima A. ischemia restores equilibrium oxygen delivery processes and consumption in cells, prevents disruption of transport of adenosine triphosphate; simultaneously, it activates glycolysis, which proceeds without additional consumption of oxygen.As a result of a decrease in the concentration of carnitine, the synthesis of gamma-butyrobetaine is enhanced, which has vasodilating properties. The mechanism of action determines the variety of pharmacological, meldonia effects: increasing efficiency, reducing symptoms of mental and physical overstrain, activation of tissue and humoral immunity, cardioprotective action. In the case of acute ischemic damage, the myocardium slows the formation of the necrotic zone, shortens the rehabilitation period. With heart failure increases contractility, myocardium, increases tolerance to physical activity, reduces the frequency of angina attacks. In acute and chronic ischemic disorders of cerebral circulation improves blood circulation in the ischemic focus, promotes redistribution of blood in favor of the ischemic site. Effective in the case of vascular and dystrophic pathology of the fundus. Characteristic is also a tonic effect on the central nervous system, elimination of functional disorders of somatic and autonomic nervous systems in patients with chronic alcoholism during the period of abstinence.