Caripazim (Caripazim)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substancePapaya Milk JuicePapaya Milk Juice
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  • Caripazim
    lyophilizate externally 
    ATC-PHARMACY, LLC     Russia
  • Caripazim
    lyophilizate externally 
    MEDFLORINA, LLC     Russia
  • Caripazim
    lyophilizate externally 
    VIFITEH, CJSC     Russia
  • Caripazim
    lyophilizate externally 
    Institute of Pharmacochemistry im.GKutateladze Academy of Sciences of Georgia     Georgia
    • Dosage form: & nbsplyophilizate for the preparation of a solution for external use
    Composition:

    Karipazim is made from Prokarypazim extract of dry, derived from Papaya lactate juice dried.

    Description:

    White with a yellowish tinge lyophilized powder or porous mass with a weak specific odor.

    Pharmacotherapeutic group:Proteolytic agent
    ATX: & nbsp

    D.03.B   Enzyme preparations

    Pharmacodynamics:

    Karipazim is made from Prokarypazim extract of dry, obtained from dried milk juice of immature fruits of this tree (papaya) - Carica papaya L., family papaevye - Caricaceae) by dissolving the dry extract in water for injection, subsequent sterile filtration of the solution and freeze-drying.

    The chemical composition of the drug is the sum of water-soluble proteolytic enzymes, the active components of which are enzymes: papin, chymopapain A, chymopapain B, peptidase A, peptidase B.

    It has proteolytic activity.The drug cleaves necrotic tissues, dilutes viscous secrets, exudates, blood clots. By action is analogous to lekosim and its constituents.

    Indications:

    Burns III-a degree (to accelerate the rejection of the strings and cleanse the wound surfaces from the remains of purulent-necrotic tissues.

    Contraindications:

    Hypersensitivity to the components of the drug. Pregnancy, lactation.

    Dosing and Administration:

    Outwardly, in the form of 0.5%, 1 % or 2% of solutions depending. from the thickness of the scab. Solutions are prepared at 0.5 % solution of novocaine or 0.9% (physiological) solution of sodium chloride. To prepare 0.5%, 1% or 2% solution of the drug, the contents of the vial are diluted with 20 ml, 10 ml or 5 ml of a solution of novocaine or sodium chloride, respectively. The drug solutions are used immediately after preparation.

    A tissue moistened with a solution of the drug is applied to the burn surface and covered with a waterproof bandage. At the same time, no more than 30% of the total body surface is treated. The bandage is changed once a day or 1 time in 2 days, while removing the exfoliated necrotic tissue. The course of treatment is from 4 to 12 days.

    Side effects:

    Allergic reactions.

    Overdose:

    Overdose may increase the side effects. In these cases, desensitizing therapy (tavegil, diazolin, etc.) is performed.

    Interaction:Not described.
    Form release / dosage:

    Liofilizate for the preparation of a solution for external use.

    Packaging:To 350 PE per glass bottles with a capacity of 10 ml. Each bottle, together with the instructions for use, is placed in a pack of cardboard.
    Storage conditions:

    In a dry, dark place at a temperature of no higher than 15 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-009716/08
    Date of registration:05.12.2008
    Expiration Date:Unlimited
    The owner of the registration certificate:VIFITEH, CJSC VIFITEH, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp13.12.2017
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