Active substancePapaya Milk JuicePapaya Milk Juice Similar drugsTo uncover Caripazim lyophilizate externally ATC-PHARMACY, LLC Russia Caripazim lyophilizate externally MEDFLORINA, LLC Russia Caripazim lyophilizate externally VIFITEH, CJSC Russia Caripazim lyophilizate externally Institute of Pharmacochemistry im.GKutateladze Academy of Sciences of Georgia Georgia Dosage form: & nbsplyophilizate for the preparation of a solution for external use Composition:Each vial contains:Enzymes obtained from dried milky juice of a melon tree Carica papaya L., family papaevyh - Caricaceae with total proteolytic activity of 350PE: papain, chymopapain A, chymopapain AT, peptidase A and AT, mucolytic enzyme - lysozyme. Description:White, with a yellowish tinge, lyophilized powder or a porous mass without a smell. Pharmacotherapeutic group:Proteolytic agent ATX: & nbspD.03.B Enzyme preparations Pharmacodynamics: Proteolytic agent for external use, cleaves necrotic tissues, dilutes viscous secrets, exudate, blood clots. By action it is close to chymotrypsin and trypsin. Pharmacokinetics:When applied externally, the drug is not absorbed and does not have systemic effects on the body. The enzymes that make up Karipazima are destroyed and completely biotransformed in the liver. Indications:Burns IIIand degrees (to accelerate the rejection of the strings and purification of granulating wounds from the remains of purulent-necrotic tissues). Contraindications:Increased individual sensitivity to the drug. Pregnancy, lactation. Dosing and Administration:Outer, in the form of solutions with concentrations of 17.5 PE / ml, 35 PE / ml or 70 PU / ml, depending on the thickness of the scab. Solutions are prepared on a 0.5% solution of novocaine or 0.9% isotonic sodium chloride solution. A tissue moistened with a drug is applied to the burn surface, covered with a waterproof bandage. At the same time, no more than 30% of the total body surface is treated. The bandage is changed once a day or 1 time in 2 days, while removing the exfoliated necrotic tissue. The course of treatment is 4-12 days. Side effects:Allergic reactions. Overdose:Cases of overdose are not described. Interaction:Clinically significant interactions of caripazim with other drugs have not been established. Special instructions:The drug has no adverse effect on the ability to drive a car and work with machinery. Form release / dosage:Liofilizate for the preparation of a solution for external use of 350 PE. Packaging:1 bottle is placed in a cardboard box together with instructions for use. Storage conditions:In a dry, dark place at a temperature of 2 ° C to 8 ° C. Keep out of the reach of children. Shelf life:2 years. Do not use later than the time specified on the package. Terms of leave from pharmacies:On prescription Registration number:П N013577 / 01 Date of registration:19.05.2008 / 23.11.2015 Expiration Date:Unlimited The owner of the registration certificate:Institute of Pharmacochemistry im.GKutateladze Academy of Sciences of Georgia Institute of Pharmacochemistry im.GKutateladze Academy of Sciences of Georgia Georgia Manufacturer: & nbspInstitute of Pharmacochemistry im.GKutateladze Academy of Sciences of Georgia Georgia Information update date: & nbsp13.12.2017 Illustrated instructions × Illustrated instructions Instructions