Maxidex - instructions for use, dose, side effects, contraindications

Dexamethasone is a synthetic fluorinated glucocorticosteroid that does not possess mineral corticoid activity. Has a pronounced anti-inflammatory, antiallergic and desensitizing effect. Dexamethasone actively suppresses inflammatory processes, suppressing eosinophilic ejection of inflammatory mediators, migration of mast cells and decreasing capillary permeability, vasodilation.

Pharmacokinetics:

With topical application, it penetrates well into the corneal epithelium and conjunctiva: in the aqueous humor of the eye, therapeutic concentrations are achieved; with inflammation or damage to the mucous membrane, the penetration rate increases.

Indications:

- Inflammation of the anterior part of the eye: acute and chronic uveitis, iridocyclitis, iritis and cyclilit;

- blepharitis, keratoconjunctivitis, conjunctivitis - allergic, seasonal, catarrhal;

- prevention and treatment of inflammatory phenomena in the postoperative period;

- thermal and chemical burn (after complete epithelialization of corneal defects).

Contraindications:

- Hypersensitivity to any of the components of this drug;

- toeradite caused by Herpes simplex (dendritic keratitis), chicken pox and other viral diseases of the cornea and conjunctiva;

- mycobacterial infections of the eyes;

- fungal diseases of the eyes;

- acute purulent diseases of the eyes;

- damage to the integrity of the corneal epithelium;

- the period of breastfeeding;

- age to 18 years (safety and efficacy of the drug in children have not been studied).

Pregnancy and lactation:

Sufficient experience in the use of the drug during pregnancy is not present. It is possible to use the treatment for pregnant women on prescription of the attending physician if the expected curative effect exceeds the risk of development of possible side effects.

Dosing and Administration:

Locally.

PThe ointment of an ointment of 1-1.5 cm long is placed behind the lower eyelid 2-3 times a day.

You can combine the use of ointment and eye drops: ointment - in the evening before going to bed, eye drops - during the day.

The duration of therapy is 2-3 weeks or as recommended by a doctor.

Side effects:

With prolonged use of steroid drugs, the following can be observed:

- increased intraocular pressure with possible subsequent development of steroid glaucoma with damage to the optic nerve and the visual fields (therefore, when using preparations containing glucocorticosteroids for more than 10 days, the intraocular pressure should be measured regularly);

- formation of posterior subcapsular cataract;

- slowing down the process of wound healing (with diseases that cause thinning of the cornea, its perforation is possible).

Allergic reactions are possible.

Secondary bacterial infection may occur as a consequence of suppression of the protective reaction of the patient's body.In acute purulent diseases of the eye, glucocorticosteroids can mask or strengthen the existing infectious process.

Fungal infection of the cornea tends to occur especially often with prolonged use of steroids. The appearance of non-healing ulcers on the cornea after prolonged treatment with steroid preparations may indicate the development of fungal infestation.

Overdose:Symptoms: local manifestations are possible.

Treatment: symptomatic.

Interaction:

Interaction with other drugs is not currently known.

In the case of use with other local ophthalmic preparations, the interval between their use should be at least 10 minutes.

Special instructions:

Before using the drug, contact lenses should be removed and installed back no earlier than 20 minutes after using the drug.

If the duration of therapy is more than 2 weeks, the condition of the cornea should be monitored.

Effect on the ability to drive transp. cf. and fur:If the patient's vision is temporarily reduced after application of the drug,before its restoration it is not recommended to drive a car and engage in activities that require increased attention.

Form release / dosage:Eye ointment, 0,1%.

Packaging:

In an aluminum tube of 3.5 grams with a plastic screw cap.

One tube with instructions for use in a pack of cardboard.

Storage conditions:

At a temperature from 2 to 27 ° C, out of the reach of children.

Shelf life:

4 years.

Do not use after the expiry date shown on the package.

Terms of leave from pharmacies:On prescription

Registration number:П N013731 / 02

Date of registration:09.12.2008

Date of cancellation:2017-01-09

The owner of the registration certificate:Alkon-Kouvreur N.V. S.A.Alkon-Kouvreur N.V. S.A. Belgium

Manufacturer: & nbsp

ALCON-COUVREUR, n.v. s.a. Belgium

Representation: & nbspALKON PHARMACEUTICS LLCALKON PHARMACEUTICS LLCRussia

Information update date: & nbsp09.01.2016

Illustrated instructions

Instructions

Maxidex® (Maxidex®)