Active substanceMethionineMethionine
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  • Methionine
    pills inwards 
    MARBIOFARM, OJSC     Russia
  • Methionine
    pills inwards 
    OZONE, LLC     Russia
  • Methionine
    pills inwards 
    AVVA RUS, OJSC     Russia
  • Methionine
    pills inwards 
  • Methionine
    pills inwards 
  • Dosage form: & nbsptCovered abets shell
    Composition:

    Each tablet contains:

    Active substance - Methionine 250 mg;

    Excipients - potato starch 44,000 mg, methylcellulose 3,000 mg, stearic acid 3,000 mg;

    Shell accessories - wheat flour 18.556 mg, sucrose 62.486 mg, magnesium carbonate 18.264 mg, talc 0.496 mg, refined sunflower oil 0.097 mg, beeswax 0.097 mg, dye azorubin 0.004 mg.

    Description:

    Round, biconvex tablets, covered with a pink coating with insignificant inclusions. On the cross-section, two layers with a noticeable boundary between them are visible.

    Pharmacotherapeutic group:Metabolic means
    ATX: & nbsp

    A.05.B.A   Preparations for the treatment of liver diseases

    Pharmacodynamics:An indispensable amino acid, the donor of mobile methyl groups for the synthesis of choline, phospholipids, the realization of lipotropic effect. Participates in the synthesis of adrenaline, proteins, re-methylation reactions, deamination, decarboxylation, etc.Participates in the exchange of sulfur-containing amino acids, adrenaline, creatinine, cyanocobalamin, ascorbic and folic acids, hormones, enzymes. Has a detoxifying effect. Has a metabolic, hepatoprotective effect.
    Pharmacokinetics:It is easily absorbed in the intestines, with a small amount of urine.
    Indications:

    Diseases of the liver (hepatitis, hepatosis, cirrhosis), which occur with fatty infiltration of hepatocytes; prevention of toxic liver damage by arsenic, chloroform, benzene, alcohol; deficiency of protein of various origin in the combination therapy.

    Contraindications:

    Viral hepatitis, severe hepatic insufficiency, hepatic encephalopathy, hypersensitivity to the drug components.

    The drug is contraindicated for children under 6 years.

    Carefully:

    Renal failure (risk of hyperaemia)

    Not recommended Methionine in viral hepatitis.

    Pregnancy and lactation:

    There is no separate data.

    Dosing and Administration:

    Inside adults of 0.5-1.5 g, children over 6 years of 0.25 g - 0.5 g 3-4 times a day for 30-60 minutes before meals.

    The course of treatment 10-30 days or courses of 10 days with 10-day intervals.

    Side effects:

    Possible allergic reactions, nausea, vomiting (due to unpleasant odor and taste).

    Overdose:

    Symptoms: decrease in arterial pressure, tachycardia, disorientation.

    Treatment: symptomatic.

    Special instructions:

    The drug should be given in a balanced ratio with other amino acids.

    Unbalanced use of methionine in large doses can have a damaging effect on liver cells and other organs.

    Effect on the ability to drive transp. cf. and fur:

    The drug does not affect the ability to drive and engage in potentially dangerous activities that require increased attention and speed of mental and motor reactions.

    Form release / dosage:

    The tablets covered with a cover, 250 mg.

    Packaging:

    For 10 or 25 tablets in a contour mesh box made of polyvinylchloride film and aluminum foil printed lacquered.

    For 1, 2 or 5 contour squares, together with the instructions for use, will be prevented in a pack of cardboard.

    Storage conditions:

    In a place protected from moisture and light at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    5 years.

    Do not use the product after the expiry date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LS-001209
    Date of registration:23.03.2011 / 17.01.2018
    Expiration Date:Unlimited
    The owner of the registration certificate:AVVA RUS, OJSC AVVA RUS, OJSC Russia
    Manufacturer: & nbsp
    Representation: & nbspAVVA ENG JSC AVVA ENG JSC Russia
    Information update date: & nbsp08.05.2018
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