Metrogil Denta® (Metrogyl Denta®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceMetronidazole + ChlorhexidineMetronidazole + Chlorhexidine
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    • Dosage form: & nbsp

    Gel stomatologic

    Composition:

    Composition:

    1 g of gel contains:

    Active substances:

    Metronidazole benzoate 16.0 mg

    (equivalent to metronidazole

    .................................................. 10.0 mg)

    Chlorhexidine digluconate 20%

    solution .......................................... 2.5 mg

    (which is equivalent to chlorhexidine

    digluconate 0.5 mg)

    and auxiliary substances:

    propylene glycol 50.0 mg,

    carbomer-940 15.0 mg,

    disodium edetate 0.5 mg,

    sodium saccharinate 1.0 mg,

    levomenthol 5.0 mg,

    sodium hydroxide 4.0 mg,

    water c. demand.
    Description:

    Opalescent soft gel of white or almost white color

    Pharmacotherapeutic group:Antimicrobial agent
    ATX: & nbsp

    A.01.A.B   Antimicrobials for topical use in diseases of the oral cavity

    A.01.A.B.11   Other

    Pharmacodynamics:

    The effectiveness of the drug is due to the presence in its composition of two antibacterial components:

    a) metronidazole has antibacterial action against anaerobic bacteria that cause periodontal disease: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium fusiformis, Wolinellci recta, Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas spp.

    b) chlorhexidine - antiseptic and antimicrobial agent, effective against gram-positive and gram-negative aerobic and anaerobic bacteria (Treponema spp., Neisseria gonorrhoeae, Trichomonas spp., Chlamydia spp., Ureaplasma spp., Bacteroides fragilis). Some strains are slightly sensitive to the drug Pseudomonas spp., Proteus spp., and also resistant to acid-fast forms of bacteria, spores of bacteria. Does not interfere with the functional activity of lactobacilli.

    With topical application, Metrogil Denta gel is not practically absorbed.
    Indications:

    Infectious-inflammatory diseases of periodontal and oral mucosa: acute and chronic gingivitis; acute ulcerous-necrotic gingivitis of Vincent; acute and chronic periodontitis; juvenile periodontitis; periodontal disease complicated by gingivitis; aphthous stomatitis; cheilitis; inflammation of the oral mucosa during the wearing of prostheses; postextraction alveolitis (inflammation of the hole after tooth extraction); periodontitis, periodontal abscess (in combination therapy)

    Contraindications:

    Individual intolerance to metronidazole, chlorhexidine, as well as derivatives of nitroimidazole.Intolerance to any components that make up the drug. Children under 6 years.

    Pregnancy and lactation:

    It is not recommended to prescribe the drug to pregnant women in the first trimester of pregnancy. In the lactation period, if you need to prescribe the drug, you should decide whether to stop breastfeeding.

    Dosing and Administration:

    Locally, only for dental use.

    Adults and children over 6 years old with gum disease (gingivitis) Metrogil Denta® is applied to the gum area with a thin layer of finger or with a cotton swab 2 times a day. After applying the gel, you should refrain from drinking and eating for 30 minutes. It is not recommended to wash off the gel. The duration of treatment is an average of 7-10 days.

    With periodontitis after removal of dental deposits, periodontal pockets are treated with Metrogil Dent gel and gel application is applied to the gum area. Exposure time - 30 min. The number of procedures depends on the severity of the disease. In the future, the patient's gel can be applied on his own: Metrogil Denta® is applied to the gum area 2 times a day for 7-10 days.

    With aphthous stomatitis, Metrogil Dent is applied to the affected area of ​​the oral mucosa 2 times a day for 7-10 days.

    To prevent exacerbations of chronic gingivitis and periodontitis, Metrogil Denta gel is applied to the gum area 2 times a day for 7-10 days. Preventive courses of treatment are carried out 2-3 times a year.

    For the prevention of postextraction alveolitis after tooth extraction, the well is treated with Metrogil Denta gel, then the gel is applied 2-3 times a day for 7-10 days.

    Side effects:

    With topical application of Metrogil Denta gel, allergic reactions (skin rash, itching, urticaria) and headache can be observed.

    Overdose:Accidental or intentional ingestion of a large amount of gel may become cause increased side effects, mainly due to metronidazole (chlorhexidine practically not absorbed from the gastrointestinal tract). There may be: nausea, vomiting, dizziness, in more severe cases - paresthesia and seizures. Treatment: gastric lavage, symptomatic therapy if necessary.
    Interaction:

    When topical application in the recommended doses of systemic interaction of the gel Metrogil Denta ® with other medicines is not revealed.

    Special instructions:The use of Metrogyl Denta gel is not replaces hygienic teeth cleaning, therefore during the course of treatment dentifrice should be continued.
    If the medicine has become unusable or the expiration date has expired, do not throw it into sewage or into the street! Place the medicine in a bag and put in a a garbage container. These measures will help protect the environment
    Form release / dosage:

    Gel stomatologic

    Packaging:

    - By 5 g, 10 g or 20 g in a plastic laminated tube, the neck of which is sealed with aluminum foil, laminated with polyethylene and with a screw cap made of polypropylene. One tube in a cardboard box with instructions for use.

    - By 5 g, 10 g or 20 g in a plastic laminated tube, the neck of which is sealed with aluminum foil, laminated with polyethylene and with a screw cap of polypropylene with a lip for perforating the foil. One tube in a cardboard box with instructions for use.

    - By 5 g, 10 g or 20 g in an aluminum tube, the neck of which is sealed with an aluminum membrane and with a screw-on lid of polyethylene with a protrusion for perforating the membrane. One tube in a cardboard box with instructions for use.

    Storage conditions:At a temperature of no higher than 25 ° C. Keep out of reach of children.
    Shelf life:

    3 years. Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:П N015982 / 01
    Date of registration:12.08.2009
    The owner of the registration certificate:Johnson & Johnson, LLC Johnson & Johnson, LLC Russia
    Manufacturer: & nbsp
    Representation: & nbspJohnson & Johnson LLC Johnson & Johnson LLC Russia
    Information update date: & nbsp26.09.2015
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