Active substanceBenzyldimethyl [3- (myristoylamino) propyl] ammonium chloride monohydrateBenzyldimethyl [3- (myristoylamino) propyl] ammonium chloride monohydrate
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  • Miraminol
    solution locally externally 
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  • Dosage form: & nbspsolution for local and external use
    Composition:

    Composition per 1 liter:

    Active substance: benzyldimethyl-myristoylamino-propylammonium chloride monohydrate (in terms of benzyldimethyl-myristoylamino-propylammonium chloride) 0.1 g

    Excipient: purified water - up to 1 liter.

    Description:Colorless transparent liquid, foaming with shaking.
    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.J   Quaternary ammonium compounds

    S.01.A.X   Other antimicrobials

    Pharmacodynamics:

    Miraminol has a broad spectrum of antimicrobial activity, including hospital strains resistant to antibiotics.

    The drug has a pronounced bactericidal action against Gram-positive (Staphylococcus spp., Streptococcus spp., Streptococcus pneumoniae and etc.), gram-negative (Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp. and etc.),

    aerobic and anaerobic bacteria, defined as monocultures and microbial associations, including hospital strains with multidrug resistance to antibiotics.Has an antifungal effect on Ascomycetes of the genus Aspergillus and Penicillium, yeast mushrooms (Rhodotorula rubra, Torulopsis gabrata etc.) and yeast-like fungi (Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur) etc.), dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini. Trichophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseum. Microsporum canis etc.), as well as other pathogenic fungi, in the form of monocultures and microbial associations, including a fungal microflora with resistance to chemotherapeutic drugs. It has an antiviral effect, is active against complex viruses (herpes viruses, human immunodeficiency virus, etc.). Miraminol acts on causative agents of sexually transmitted diseases (Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae and etc.).

    Effectively prevents infection of wounds and burns. Activates regeneration processes. Stimulates protective reactions at the site of application, by activating the absorbing and digesting function of phagocytes, potentiates the activity of the monocyte-macrophage system. Has a pronounced hyperosmolar activity, as a result of which it stops wound and perifocal inflammation, absorbs purulent exudate, promotes the formation of a dry scab.Does not damage granulation and viable skin cells, does not inhibit marginal epithelization. Does not have a local irritant effect and allergic properties.

    Pharmacokinetics:

    When topical application does not have the ability to be absorbed through the skin and mucous membranes.

    Indications:

    Otorhinolaryngology: complex treatment of acute and chronic otitis, sinusitis, tonsillitis, laryngitis, pharyngitis.

    In children aged 3 to 14 years is used for the complex treatment of acute pharyngitis and / or exacerbation of chronic tonsillitis.

    Dentistry: treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis. Hygienic treatment of removable dentures.

    Surgery, traumatology: prevention of suppuration and treatment of purulent wounds. Treatment of purulent-inflammatory processes of the musculoskeletal system.

    Obstetrics-Gynecology: prevention and treatment of suppuration of postpartum injuries, crotch and vagina wounds, postpartum infections, inflammatory diseases (vulvovaginitis, endometritis).

    Combustiology: treatment of superficial and deep burns of II and ША degree, preparation of burn wounds to dermatoplasty.

    Dermatology, venereology: treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, foot mycoses.

    Individual prevention of sexually transmitted diseases (syphilis, gonorrhea, chlamydia, trichomoniasis, genital herpes, genital candidiasis, etc.).

    Urology: complex treatment of acute and chronic urethritis and urethroprostatitis specific (chlamydia, trichomoniasis, gonorrhea) and nonspecific nature.

    Contraindications:

    Individual intolerance to the drug.

    Application during pregnancy and during breastfeeding

    Pregnancy and lactation:The use of the drug during pregnancy and during breastfeeding is possible if the intended benefit to the mother exceeds the potential risk to the fetus and the baby. It is necessary to consult a doctor.
    Dosing and Administration:

    The drug is ready for use.

    Notes on the use of a spray gun package:

    - Remove the cap from the vial, remove the applicator from the 50 ml bottle urological.

    - Remove the supplied spray nozzle from the protective packaging.

    - Attach the spray nozzle to the vial.

    - Press the nozzle again to activate the nozzle.

    Instructions on the use of a 50 ml or 100 ml package with a gynecological attachment:

    - Remove the cap from the vial.

    - Remove the attached gynecological attachment from the protective package.

    - Attach the gynecological attachment to the vial without removing the urologic applicator.

    Otorhinolaryngology

    With purulent sinusitis - during puncture the maxillary sinus is washed with a sufficient amount of the drug. Tonsillitis, pharyngitis and laryngitis are treated with a gargling and / or irrigation with a spray nozzle, 3-4 times a day, 3-4 times a day. The amount of preparation per rinse is 10-15 ml.

    Children. In acute pharyngitis and / or exacerbation of chronic tonsillitis, irrigation of the pharynx is carried out with the help of a spray nozzle. Children aged 3-6 years: a single press on the head of the spray nozzle (3-5 ml per irrigation), 3-4 times a day; children aged 7-14 years with a double tap (5-7 ml per irrigation), 3-4 times a day; children over 14 years 3-4 times pressing (10-15 ml per irrigation), 3-4 times a day. The duration of therapy is from 4 to 10 days, depending on the timing of the onset of remission.

    Stomatology

    With stomatitis, gingivitis, periodontitis, it is recommended to rinse the oral cavity with 10-15 ml of the drug, 3-4 times a day.

    Surgery, Traumatology, Combustiology

    With a preventive and curative purpose irrigate the surface of wounds and burns, loose wounds and fistulous swabs are stuffed, gauze tampons moistened with the drug are fixed. The treatment procedure is repeated 2-3 times a day for 3-5 days. The method of active drainage of wounds and cavities with a daily consumption of up to 1 liter of the drug is highly effective.

    Obstetrics, gynecology

    For the prevention of postpartum infection, it is used in the form of vaginal irrigation before childbirth (5-7 days), at birth after each vaginal examination and in the postpartum period 50 ml of the drug in the form of a tampon with an exposure of 2 hours for 5 days. For the convenience of vaginal irrigation, the use of a gynecological attachment is recommended. The contents of the vial with the help of a gynecological attachment to enter the vagina and irrigate.

    When delivering women by caesarean section, immediately before the operation, the vagina is treated, during surgery - the uterine cavity and the incision on it, and in the postoperative period, tampons moistened with the drug are injected into the vagina with exposure 2 hours for 7 days.Treatment of inflammatory diseases is carried out by the course for 2 weeks by intra-vaginal administration of tampons with the drug, as well as by drug electrophoresis.

    Venerology

    For the prevention of sexually transmitted diseases the drug is effective if it is used no later than 2 hours after sexual intercourse. The contents of the vial with the help of an urological applicator to enter the urethra for 2-3 minutes: men (2-3 ml), women (1-2 ml) and the vagina (5-10 ml). For convenience, the use of a gynecological attachment is recommended. Treat the skin of the inner surfaces of the hips, pubic area, genitals. After the procedure, it is recommended not to urinate for 2 hours.

    Urology

    In the complex treatment of urethritis and urethroprostatitis, 2-3 ml of the drug is injected into the urethra 3-2 times a day, the course is 10 days.

    If there is no improvement after treatment, or the symptoms worsen, or new symptoms appear, it is necessary to consult a doctor. Use the drug only according to the method of administration and the doses specified in the instructions.

    Side effects:

    In some cases, at the site of application, a feeling of slight burning that can go away by itself, after 15-20 seconds, does not need to be canceled. Allergic reactions.

    If you have side effects indicated in the instructions, or they are aggravated, or you notice any other side effects not listed in the instructions, tell your doctor.

    Overdose:

    Data on drug overdose are absent.

    Interaction:

    With simultaneous use with antibiotics and antimycotics, there has been an increase in their antibacterial and antifungal properties.

    If you use the above or other medicines (including OTC drugs) before using Miraminol, consult your doctor.

    Effect on the ability to drive transp. cf. and fur:

    Does not affect the ability to drive vehicles and other mechanisms.

    Form release / dosage:

    Solution for local and external use 0,01%.

    Packaging:25, 40, 50, 60, 70, 80, 100, 150, 200, 500, 1000 ml into the plastic bottles, polyethylene, polyethylene terephthalate or plastic dropper bottles, ukuporennye applicator urological screw cap or plugs, polymer or stoppers with sealing elements or stoppers, droppers and polymer caps or ukuporennyh caps polyethylene threaded (ssealing element or with a sealing element and a stick with a brush or with the control of the first opening), or sealed with a spray nozzle with a cap or without a cap.

    Each bottle or bottle-dropper is glued with a label from writing paper, or label, or a self-adhesive label.

    Each vial or flask-dropper along with the instruction for use is placed in a pack of cardboard.

    By 1,3, 5, 10, 18, 20, 25, 30 l into polyethylene cans with a lid (for hospitals).

    For each canister, a label of writing paper, or a label, or a self-adhesive label is affixed.

    Each canister, together with the instruction for use, is placed in a box of corrugated cardboard (for hospitals).

    For each box paste a label from writing paper, or label, or a self-adhesive label.

    Storage conditions:

    At a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years. Do not use after expiry date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-004621
    Date of registration:26.12.2017
    Expiration Date:26.12.2022
    The owner of the registration certificate:TULA PHARMACEUTICAL FACTORY, LTD. TULA PHARMACEUTICAL FACTORY, LTD. Russia
    Manufacturer: & nbsp
    Information update date: & nbsp24.01.2018
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