Active substanceTetrisolinTetrisolin
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  • Dosage form: & nbspeye drops
    Composition:

    1 ml of solution contains active substance tetrahydrozoline hydrochloride (tetrisoline hydrochloride) 0.5 mg; Excipients - Benzalkonium chloride 0.1 mg, disodium edetate, sodium chloride, boric acid, sodium tetraborate (borax), water for injection.

    Description:A clear, colorless solution.
    Pharmacotherapeutic group:Alpha-adrenomimetic
    ATX: & nbsp

    S.01.G.A.02   Tetrisolin

    Pharmacodynamics:

    Alpha-adrenostimulant, it has a vasoconstrictive and anticongestive action. The vasoconstrictor effect without secondary reactive hyperemia develops within a few minutes and persists for 4-8 hours. In local applications, systemic absorption is low.

    Indications:

    Edema of the conjunctiva, secondary hyperemia with allergic eye diseases, irritation of the conjunctiva.

    Hyperemia and / or edema of the conjunctiva caused by various non-specific causes: state after tonometry, dust, cigarette smoke, smog, swimming, reading, driving.

    Contraindications:

    Hypersensitivity to one of the components of the drug, glaucoma, children's age (up to 6 years), endothelial-epithelial dystrophy of the cornea, pregnancy and lactation.

    Carefully:Arterial hypertension, arrhythmias, aneurysm, thyrotoxicosis, pheochromocytoma, diabetes mellitus, severe organic diseases of the heart and blood vessels (including coronary heart disease); period of treatment with MAO inhibitors and other drugs that increase blood pressure.
    Dosing and Administration:

    Locally. 1-2 drops in each conjunctival sac 2-3 times a day.

    If the improvement does not occur within 48 hours, further reception should be discontinued and consult a doctor.

    Side effects:

    Mydriasis, increased intraocular pressure, reactive hyperemia, lacrimation, burning sensation in the eye.

    Systemic effects (possible with the administration of a large amount of the drug): headache, nausea, drowsiness, weakness, tremor, dizziness, insomnia, palpitations, tachycardia, hyperglycemia, increased blood pressure, cardiac dysfunction, allergic reactions.

    Overdose:

    Symptoms: mydriasis, cyanosis, fever, seizures, arrhythmias, increased blood pressure, pulmonary edema, dyspnea, cardiac arrest. Excessive general absorption of imidazole derivatives can lead to central nervous system depression, accompanied by drowsiness, hypothermia, bradycardia, collapse, apnea and coma. The risk of overdose symptoms associated with drug absorption is high in young children, especially if swallowed.

    Treatment: the antidote is unknown. Assign Activated carbon, gastric lavage, inhalation of oxygen, antipyretic and antiepileptic agents. To reduce blood pressure - fentolamine 5 mg on physiological solution slowly in / in or 100 mg orally.

    Interaction:Incompatible with MAO inhibitors, tricyclic antidepressants, maprotiline (the possibility of developing a hypertensive crisis), as with inhalational anesthetics (eg cyclopropane, halothane and other halogenated anesthetics that can cause ventricular fibrillation).
    Special instructions:

    Use within 30 days after opening the vial.

    Avoid prolonged use and overdose, especially in children.

    If eye disease is not an obstacle to wearing contact lenses, they should be removed before instillation of the drug and set after about 15 minutes. Avoid direct contact of eye drops with soft contact lenses, considering the risk of their transparency being impaired.

    If the condition does not improve within 48 hours, or irritation and hyperemia of the eyes persist or build up, you should cancel the drug and consult a doctor. If you have intense pain in the eyes, headache, loss of vision, sudden appearance of "floating" spots before your eyes, redness of the eyes, pain when exposed to light or doubling in the eyes, you should immediately consult a doctor.

    Effect on the ability to drive transp. cf. and fur:During the period of treatment, it is necessary to refrain from engaging in potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions (the possibility of developing a visual impairment).
    Form release / dosage:
    Eye drops 0.05%.
    Packaging:To 10 ml in a bottle of colorless glass, ukuporenny rubber stopper with a metal cap. 1 bottle together with a dispensing nozzle and instructions for medical use are placed in a cardboard pack.
    Storage conditions:At a temperature of 15 to 25 ° C, protected from light, out of reach of children.
    Shelf life:

    3 years.

    Do not use after the expiry date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LS-001813
    Date of registration:16.09.2011 / 29.09.2015
    Expiration Date:Unlimited
    The owner of the registration certificate:Hemofarm ADHemofarm AD Serbia
    Manufacturer: & nbsp
    Representation: & nbspNizhpharm, JSCNizhpharm, JSCRussia
    Information update date: & nbsp02.06.2018
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