Sodium thiosulfate - instructions for use, dose, side effects, contraindications

When introduced into the body has detoxification effect. When the compounds are poisoned with arsenic, mercury, lead forms non-poisonous sulfites. When poisoned with cyanides, it forms less toxic rhodanous compounds.

Pharmacokinetics:

After intravenous use, it spreads into the extracellular fluid. It is excreted from the body with urine. The half-life is 0.65 hours.

Indications:

Poisoning by arsenic, mercury, lead, hydrocyanic acid and its salts, iodine and bromine salts.

Contraindications:

Hypersensitivity, children under 18 years of age (due to lack of experience of use).

Pregnancy and lactation:During pregnancy, the drug is used solely for life indications. During lactation should refrain from breastfeeding.

Dosing and Administration:

The drug is administered intravenously with 5-10 ml of a solution of 300 mg / ml; when poisoning with cyanide compounds, a single dose is increased to 50 ml of a solution of 300 mg / ml.

Side effects:

Allergic reactions.

Overdose:

Cases of overdose are unknown.

Interaction:

Strongly forbid contact of sodium thiosulfate with nitrates, potassium permanganate.

Special instructions:

When cyanide poisoning is recommended, the simultaneous administration of sodium hyposulfite and sodium nitrite.

Form release / dosage:

Solution for intravenous administration 300 mg / ml.

Packaging:

For 10 ml of the drug into neutral glass ampoules.

For 10 ampoules together with instructions for medical use and scarifier ampullum in a cardboard bundle with cardboard partitions,or 5 or 10 ampoules in a contiguous cell pack of a polyvinyl chloride film.

When using ampoules with a notch or a fracture ring, the scarifier is not inserted.

For 1 or 2 contour pack together with instructions for medical use in a cardboard box.

Storage conditions:

Store in a dark place at a temperature of no higher than 20 ° C. Keep out of the reach of children.

Shelf life:

5 years. Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:On prescription

Registration number:LSR-005204/09

Date of registration:29.06.2009

Expiration Date:Unlimited

The owner of the registration certificate:ESKOM NPK, OAO ESKOM NPK, OAO Russia

Manufacturer: & nbsp

ESKOM NPK, OAO Russia

Information update date: & nbsp25.05.2018

Illustrated instructions

Instructions

Sodium thiosulfate (Sodium thiosulfate)