Nazosprey - instructions for use, dosage, side effects, contraindications

Excipients: benzalkonium chloride 0.5 mg, boric acid 17.2 mg, disodium edetate dihydrate 0.1 mg, sodium tetraborate decahydrate 0.02 mg, water purified to 1 ml.

Description:

Transparent colorless or slightly colored solution.

Pharmacotherapeutic group:anticonvulsant - alpha-adrenomimetic

ATX: & nbsp

S.01.G.A.04 Oxymetazoline

Pharmacodynamics:

Oxymetazoline is an alpha-adrenostimulator for topical application. Has vasoconstrictive effect. With intranasal application reduces edema of the mucous membrane of the upper respiratory tract, which leads to the relief of nasal breathing and the opening of the mouths of the paranasal sinuses and Eustachian tubes. The effect of the drug begins 10-15 minutes after application and lasts for 10-12 hours.

Pharmacokinetics:

With topical application, systemic absorption is low.

Indications:

- To facilitate nasal breathing in the treatment of acute respiratory diseases accompanied by rhinitis;

- allergic rhinitis;

- vasomotor rhinitis;

- for restoration of drainage with inflammation of the paranasal sinuses of the nasal cavity, eustachiitis, otitis media;

- for elimination of edema before diagnostic manipulations in the nasal cavity.

Contraindications:

- Hypersensitivity to oxymetazoline or other components that make up the drug;

- Atrophic rhinitis;

- children's age till 6 years;

- Pregnancy;

lactation period.

Carefully:

In patients taking monoamine oxidase inhibitors (MAO) (including up to 14 days after their withdrawal); in patients with concomitant cardiovascular diseases (arterial hypertension, ischemic heart disease, chronic heart failure, tachycardia, arrhythmias); with hyperthyroidism, diabetes, pheochromocytoma, prostatic hyperplasia with clinical manifestations, angle-closure glaucoma, increased intraocular pressure, chronic renal failure; in patients taking tricyclic antidepressants and bromocriptine.

Dosing and Administration:

Adults and children over 12 years of age - 2-3 injections in each nostril with an interval of 10-12 hours. Children from 6 to 12 years - 1 injection in each nasal passage 2 times a day. Do not use the drug more than 2 times a day.

For diagnostic purposes - after cleaning the nose in each nasal passage 3-4 injections or insert a swab moistened with the drug, and leave for 1-2 minutes.

It is not recommended to use the drug for more than 3 days. With frequent or prolonged use of the drug, a feeling of difficulty in nasal breathing may reappear or worsen. If these symptoms appear, discontinue treatment and consult a doctor.

When injecting, it is not recommended to tilt the head back or spray in the "lying" position.

Side effects:

Transient dryness and burning sensation of the mucous membrane of the nasal cavity, dryness of the mucous membrane of the oral cavity and throat, sneezing; increased blood pressure, increased anxiety, nausea, dizziness, headache, insomnia, palpitations, sleep disturbances.

With prolonged use (more than 7 days) - tachyphylaxis, reactive hyperemia of the mucosa and atrophy of the mucous membrane of the nasal cavity.

Overdose:

Symptoms: tachycardia, increased blood pressure, suppression of the central nervous system.

Treatment: symptomatic.

Interaction:

Slows the absorption of local anesthetic drugs (lengthens their action in the conduct of surface anesthesia).

Joint use of other vasoconstrictive drugs increases the risk of side effects.

With simultaneous use of MAO inhibitors (including the period within 14 days after their withdrawal), tricyclic antidepressants and bromocriptine - the risk of increasing blood pressure.

Special instructions:

It is not recommended to use more than 3 days without consulting a doctor. Recommended not more than 2 times a day.

May have a resorptive effect.

With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and therefore, if long-term treatment is necessary, it is recommended after 5-7 days of use to take a break for several days. Avoid contact with the eyes.

Effect on the ability to drive transp. cf. and fur:In connection with possible systemic reactions, such as dizziness, during the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities requiring increased attention and speed of psychomotor reactions.

Form release / dosage:

Spray nasal, 0.05%.

Packaging:

For 15 ml in polymer bottles with a spray and with a control ring of the first opening.

1 bottle with instructions for use in a pack of cardboard.

Storage conditions:

Store in a dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-000607

Date of registration:21.09.2011

The owner of the registration certificate:LEKKO, ZAO LEKKO, ZAO Russia

Manufacturer: & nbsp

Pharmaceutical firm LEKKO, ZAO Russia

Representation: & nbspLEKKO ZAO LEKKO ZAO Russia

Information update date: & nbsp11.08.2015

Illustrated instructions

Instructions

Nazosphere (Nazospray)