Active substanceIdebenonIdebenon
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  • Dosage form: & nbsptoapsules
    Composition:

    1 capsule contains:

    active substance: idebenone 30 mg or 45 mg;

    Excipients: potato starch, lactose (milk sugar), microcrystalline cellulose, povidone (polyvinylpyrrolidone), crospovidone (Polyplasdone X-El-10), magnesium stearate.

    Composition of hard gelatin capsule

    for a dosage of 30 mg: titanium dioxide (E171), dye quinoline yellow (E 104), dye sunset yellow sunset (E110), gelatin;

    for a dosage of 45 mg: titanium dioxide (E171), iron oxide red (E 172), iron oxide black (E 172), dye quinoline yellow (E 104), dye sunset yellow sunset (E110), azorubin (E 122), gelatin.

    Description:

    For a dosage of 30 mg - hard gelatin capsules number 1 of yellow color.

    For a dosage of 45 mg - Hard gelatin capsules № 0 - the case of yellow color, the lid of brown color.

    The content of capsules is a granulate containing granules or powder of yellow or yellow-orange color with orange and white impregnations.

    Pharmacotherapeutic group:Nootropic remedy
    ATX: & nbsp

    N.06.B.X.13   Idebenon

    Pharmacodynamics:

    Nootropic agent, has a metabolic and trophic effect. Increases metabolic processes in the brain by activating the synthesis of glucose and adenosine triphosphate (ATP), improves blood circulation and oxygenation of brain tissue, promotes the excretion of lactates; increases the intensity and speed of neurophysiological reactions of brain structures. Slowing down peroxidation lipids, protects the membranes of neurons and mitochondria from damage. Since the first days of admission shows anti-asthenic, psychostimulating and antidepressant effect, nootropic effect is manifested after 3-4 weeks of admission.

    Pharmacokinetics:

    Absorption is fast and high; Time to reach the maximum concentration in the blood plasma (TCmax) - 4 hours Penetrates through the blood-brain barrier in significant quantities and is distributed in the brain tissues. Do not cumulate. It is excreted by the kidneys.

    Indications:

    - Psycho-organic syndrome on the background of cerebral circulation and age-related involuntary changes in the brain;

    - Cerebroasthenic disorders of vascular, traumatic, psychogenic (neurasthenia) etiology: impaired memory and / or attention, decreased intellectual productivity and general activity, emotional instability;

    - Asthenic and asthenodepressive syndrome, moderately expressed depressive syndrome; dizziness, noise in the ears.

    Contraindications:

    Hypersensitivity, chronic renal failure.

    Carefully:BVariability, lactation period.
    Dosing and Administration:

    Inside, 30-45 mg 2-3 times a day, after meals (the last reception - up to 17 hours).

    The course of treatment is 1,5-2 months. If necessary, 2-3 courses a year.

    Side effects:

    Allergic reactions; disturbance of falling asleep, psychoemotional agitation, headache, dyspepsia.

    Overdose:

    Symptoms: increased severity of side effects.

    Treatment: If necessary, designate Activated carbon and conduct symptomatic therapy.

    Effect on the ability to drive transp. cf. and fur:During the treatment period it is necessary to refrain from driving motor vehicles and practicing other potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.
    Form release / dosage:

    Capsules, 30 mg and 45 mg.

    Packaging:

    10 capsules per contour cell package.

    For 30 capsules in a jar of light-protective glass or in a jar, or a bottle of polymer materials.

    Each jar, bottle, or 1, 2, 3, 6 or 12 contour mesh packages together with instructions for use in a pack of cardboard.

    Storage conditions:

    In a dry place, at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-000173/08
    Date of registration:23.01.2008 / 13.10.2015
    Expiration Date:Unlimited
    The owner of the registration certificate:VEROPHARM SA VEROPHARM SA Russia
    Manufacturer: & nbsp
    Representation: & nbspVEROPHARM, AO VEROPHARM, AO Russia
    Information update date: & nbsp27.06.2018
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