Clinical and pharmacological group: & nbsp
Nootropics
Included in the formulation
Pharmacodynamics:Has a structural similarity with coenzyme Q10. Improves the delivery of oxygen to the brain tissues, activates metabolic processes in the brain: synthesis of glucose and ATP, enhances the elimination of lactate. Protects membranes of neurons and mitochondria from damage, slows lipid peroxidation. Has a modulating effect on the brain stem structures.
Has anti-asthenic, psychostimulating, antidepressant effect.
Pharmacokinetics:After oral administration, the empty stomach is completely absorbed in the gastrointestinal tract. The maximum concentration in the blood plasma is reached after 4 hours. Penetrates through the blood-brain barrier.
The therapeutic effect develops in 20-25 days after the beginning of admission. Metabolism in the liver.
The half-life is 18 hours. Elimination by the kidneys.
Indications:It is used for the treatment of psycho-organic syndrome on the background of cerebral circulation disturbances, with age-related involuntary changes in the brain, cerebrosthenic disorders of traumatic, vascular, psychogenic etiology, asthenic syndrome, emotional instability,moderately expressed depressive syndrome, dizziness, noise in the ears.
V.F00-F09.F07 Personality and behavioral disorders due to illness, damage or dysfunction of the brain
V.F00-F09.F07.2 Postcontasia syndrome
V.F40-F48.F48.0 Neurasthenia
VIII.H80-H83.H81 Violations of the vestibular function
VIII.H90-H95.H93.0 Degenerative and vascular diseases of the ear
IX.I60-I69.I67.2 Cerebral atherosclerosis
IX.I60-I69.I69 Effects of cerebrovascular disease
Contraindications:Chronic renal failure, individual intolerance, children under 18 years.
Carefully:Pregnancy and lactation.
Pregnancy and lactation:Recommendations for FDA - Category B. It is used in pregnancy and lactation in cases where the expected effect exceeds the risk for the fetus and the newborn.
Dosing and Administration:Inside for 30 mg 2-3 times a day after meals, the last reception - up to 17 hours. The course of treatment up to 2 months. If necessary, 2-3 courses are conducted within one year.
The highest daily dose: 90 mg.
The highest single dose: 30 mg.
Side effects:Central and peripheral nervous system: headache, agitation, insomnia, hallucinations.
Digestive system: dyspeptic disorders.
Allergic reactions.
Overdose:Cases of overdose are not described.
Treatment is symptomatic.
Interaction:Not described.
Special instructions:Patients receiving idebenon, it is recommended to exercise caution when driving vehicles and working with moving machinery.