From the gastrointestinal tract: gastralgia, nausea, diarrhea, flatulence, increased activity of "liver" transaminases,cholestatic jaundice, pseudomembranous colitis, colitis (including hemorrhagic), decreased appetite, vomiting, constipation, abdominal pain, hyperbilirubinemia, dryness of the oral mucosa, hepatitis.
From the cardiovascular system: tachycardia, collapse, ventricular arrhythmia, including arrhythmia, ventricular tachysystolic type "pirouette", increase or decrease in blood pressure, lengthening of the interval QT.
From the side of the nervous system: headache, insomnia, nervousness, tremor, convulsions, numbness and paresthesia of the limbs, intense dreams, anxiety, arousal, depression, hallucinations, increased intracranial pressure, insomnia, nervousness, epileptic seizures, extrapyramidal disorders, sensory or sensory peripheral neuropathy, impaired coordination of movement, violation of color perception, taste disorders, impaired sense of smell, hearing and balance, dizziness, lack of confidence in movements, nightmares ", dreams, phobias, confusion, drowsiness, psychotic reactions with suicidal tendencies, temporary loss of consciousness, diplopia, perversion of taste sensations,
From the musculoskeletal system: tendonitis, arthralgia, tendosinovitis, pain in the extremities, rhabdomyolysis, myalgia, tendon rupture, muscle stiffness, muscle weakness.
Allergic reactions: skin rash, hives, allergic nephritis, fever, bronchospasm; multiforme exudative erythema (including Stevens-Johnson syndrome) and toxic epidermal necrolysis (Lyell's syndrome), vasculitis, anaphylactic shock, pruritus, allergic pneumonitis, eosinophilia, angioedema, photosensitivity, itching of the vulva in women.
On the part of the blood: leukopenia, anemia (including aplastic and hemolytic), pancytopenia, agranulocytosis, thrombocytopenia.
On the part of the skin: pinpoint hemorrhages (petechiae), papular rash with a cortex, indicating a vascular lesion (vasculitis), bullous hemorrhagic dermatitis.
From the side of the urinary system: acute interstitial nephritis, hypercreatininaemia, dysuria, acute renal failure, impaired renal function, increased urea concentration, urinary retention,
Other: intestinal dysbacteriosis, hypoglycemia (in patients with diabetes mellitus
), chest pain, asthenia, photosensitivity, nosebleeds, thirst, pharyngitis, dry cough, superinfection, vaginitis, fatigue, general weakness, vaginal discharge, weight loss, rhinitis, acute porphyria (in patients with porphyria).