Efenafetat (Etofenamatum)

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
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Clinical and pharmacological group: & nbsp

NSAIDs - Fenamates

Included in the formulation
  • Revmond
    spray externally 
    Honey Manufacuring GmbH     Germany
  • Revmond
    gel externally 
    Honey Manufacuring GmbH     Germany
  • Revmond
    emulsion externally 
    Honey Manufacuring GmbH     Germany
  • Revmond
    cream externally 
    Honey Manufacuring GmbH     Germany
    • АТХ:

    M.02.A.A.06   Efenafetat

    Pharmacodynamics:

    NSAIDs for external use. Has a local anti-inflammatory and analgesic effect. It inhibits cyclooxygenase, inhibits the biosynthesis of prostaglandins from arachidonic acid. Partially absorbed from the skin surface.

    Pharmacokinetics:

    In blood, it binds to proteins by 98-99%. Bioavailability is about 20%. Renal failure does not affect the concentration in the plasma.

    Indications:

    Rheumatic diseases of soft tissues and musculoskeletal system, myositis, myalgia, lumbago, sciatica, tendosinovitis, bursitis, bruises, sprains, degenerative diseases of the spine and joints (spondylosis, arthrosis).

    ICD-10

    VI.G50-G59.G54.1   Lesions of the lumbosacral plexus

    XIII.M05-M14.M13.9   Arthritis, unspecified

    XIII.M05-M14.M06.9   Rheumatoid arthritis, unspecified

    XIII.M05-M14.M10   Gout

    XIII.M45-M49.M47   Spondylosis

    XIII.M50-M54.M54.3   Sciatica

    XIII.M60-M63.M60   Myositis

    XIII.M70-M79.M71   Other bursopathies

    XIII.M70-M79.M77.9   Other specified intesopathy

    XIII.M70-M79.M79.0   Rheumatism, unspecified

    XIX.T08-T14.T14.3   Dislocation, stretching and overstrain of the capsular-ligamentous apparatus of the joint of the unspecified area of ​​the body

    XIII.M70-M79.M79.1   Myalgia

    XIX.T08-T14   Injuries to the unspecified part of the trunk, limb or body region

    Contraindications:

    Hypersensitivity (including other derivatives of anthranilic and flufenamic acid and other NSAIDs). Pregnancy, children's age.

    Carefully:

    Avoid getting the drug on the damaged and eczema-affected skin.

    Pregnancy and lactation:

    Category by FDA not determined. Do not use during pregnancy.

    Nursing mothers should refuse breastfeeding for the period of treatment.

    Dosing and Administration:

    Naturally, a strip of gel 5-10 cm long (1650-3300 mg) is rubbed into the skin above the area of ​​the pathological process. The course is from several days to several months.

    Side effects:

    Redness of the skin, itching, burning sensation; very rarely - dermatitis.

    Overdose:

    Symptoms: headache, dizziness, discomfort in the epigastric region. Treatment: symptomatic.

    Interaction:

    Not described.

    Special instructions:

    If accidentally the skin contains the contents of one or more tubes, excess gel (cream) should be washed off immediately.

    Instructions
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