Revmond - instructions for use, dose, side effects, contraindications

Benzyl alcohol 20.0 mg; bentonite 15.0 mg; cetyl alcohol 10.0 mg; citric acid 1.8 mg; diisopropyl adipate 130.0 mg; glyceride monostearate 33.0 mg; macrogol stearate 50.0 mg; sodium citrate dihydrate 7.3 mg; purified water 632.9 mg.

Description:Homogeneous emulsion of white color.

Pharmacotherapeutic group:Non-steroidal anti-inflammatory drug (NSAID)

ATX: & nbsp

M.02.A.A.06 Efenafetat

Pharmacodynamics:

Revmon emulsion for external use contains 10% (by weight) of ethofenamate, which has pronounced anti-inflammatory and analgesic properties. Efenafetat - a non-steroidal anti-inflammatory drug whose action is based on the fact that it indiscriminately suppresses cyclooxygenase type 1 and 2, disrupts the metabolism of arachidonic acid. As a result, the synthesis of prostaglandins is inhibited and the formation of inflammatory mediators is reduced. Efenafetat has a lipophilic nature, which causes its good penetration through the skin. Concerning etofenamate is used mainly in preparations intended for external use.

Etophenamate penetrates the skin and is distributed in the affected tissue, in which it reaches therapeutic concentrations. The maximum concentrations of ethofenamate in plasma (19-31 ng / ml) are achieved after a single application of 3 g of rheumont emulsion through 12-24 hours after application. The relative bioavailability of the drug does not exceed 20%. Efenafetat is excreted by the kidneys and through the intestine in the form of its metabolites and their compounds.

Indications:

A rheumont emulsion for external use is indicated in the following cases:

- closed injuries, bruises, sports injuries, injuries of soft tissues and joints;

- osteoarthritis, periarthritis of the shoulder joint, epicondylitis, lumbago;

- ankylosing spondylitis, tendonitis, tenosynovitis, and peritendinitis.

Contraindications:

Individual hypersensitivity to one of the components of the drug, to acetylsalicylic acid or other NSAIDs, anamnestic data on the attack of bronchial obstruction, rhinitis; urticaria after taking acetylsalicylic acid or other NSAIDs, violation of the integrity of the skin.

Rheumont Emulsion for external use is not recommended for use in children's practice, because of the lack of clinical safety data.

Carefully:Erosive-ulcerative lesions of the gastrointestinal tract, severe violations of liver and kidney function, chronic heart failure, elderly age, bronchial asthma.

Pregnancy and lactation:

Rheumont emulsion for external use is contraindicated for use during pregnancy, since it is established that etofenamate penetrates the placental barrier.

In the period of application of the drug Revmont emulsion for external use, nursing mothers should refuse breastfeeding.

Dosing and Administration:

Rheumont emulsion for external application is applied directly to the skin 3-4 times a day, spreading over as large a area as possible. The required amount of the drug depends on the size of the painful area. A single dose of the drug is 1.7-3.3 g, which corresponds approximately to the spot of the emulsion with a diameter of 3 cm. After applying the preparation, you should thoroughly wash your hands. The course of treatment is from 1 to 2 weeks to several months after consulting a doctor.

Side effects:

In rare cases, reversible allergic reactions in the form of urticaria, dermatitis, peeling, erythema, or itching may develop in the area of application of the Revmont Emulsion for external use. In this case, stop using the drug and consult a doctor.

Overdose:Information on the effects of overdose Revmont emulsion for external use is not available. With accidental ingestion, it is possible to develop systemic adverse reactions. Treatment: gastric lavage, induction of vomiting, Activated carbon, forced diuresis, symptomatic therapy. Dialysis is not effective due to the high degree of binding of etofenamate to proteins (about 99%).

Interaction:The interaction of rheumont emulsion for external use with other medications has not been established.

Special instructions:

Rheumont emulsion for external use should not be applied to damaged or eczematous inflammation of the skin, mucous membranes, including the mucous membranes of the eyes.

After applying, do not apply an occlusive bandage. With prolonged use and / or application on extensive surfaces, it is possible to develop systemic side effects due to resorptiveactions. Apply only externally.

Effect on the ability to drive transp. cf. and fur:

Revmon emulsion for external use does not affect the ability to drive vehicles and work with complex mechanisms.

Form release / dosage:

Emulsion for external use 10%.

Packaging:

100 grams of emulsion in a non-transparent bottle of polypropylene with a protective inner liner. The bottle together with the instruction for use is placed in a cardboard box.

Storage conditions:

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:4 years. Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-001387

Date of registration:20.12.2011

The owner of the registration certificate:Honey Manufacuring GmbHHoney Manufacuring GmbH Germany

Manufacturer: & nbsp

MEDA Manufacturing, GmbH Germany

Representation: & nbspHoney Manufacuring GmbHHoney Manufacuring GmbH

Information update date: & nbsp20.10.2015

Illustrated instructions

Instructions

Revmond (Revmonn)