Revmond (Revmonn)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceEfenafetatEfenafetat
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  • Revmond
    spray externally 
    Honey Manufacuring GmbH     Germany
  • Revmond
    gel externally 
    Honey Manufacuring GmbH     Germany
  • Revmond
    emulsion externally 
    Honey Manufacuring GmbH     Germany
  • Revmond
    cream externally 
    Honey Manufacuring GmbH     Germany
    • Dosage form: & nbspgel for external use
    Composition:

    for 1 g: 5% gel:

    Active ingredient:

    Efenafetat 50.0 mg

    Excipients:

    Cetomacrogol oleate 60.0 mg; isopropanol 381.0 mg; macrogol - 400 30.0 mg; Carbomer 940 10.30 mg; sodium hydroxide 0.75 mg, water 465.25 mg. gel 10%:

    Active ingredient:

    Efenafetat 100.0 mg

    Excipients:

    Cetomacrogol oleate 60.0 mg; isopropanol 380 mg; macrogol - 400 40.0 mg; Carbomer 940 18.0 mg; sodium hydroxide 0.75 mg; propylene glycol 30.0 mg; water 371.25 mg.

    Description:Homogeneous, almost colorless or slightly yellowish gel, transparent or with a slight opalescence, with a characteristic smell of isopropyl alcohol.
    Pharmacotherapeutic group:Non-steroidal anti-inflammatory drug (NSAID)
    ATX: & nbsp

    M.02.A.A.06   Efenafetat

    Pharmacodynamics:

    Rheumont gel for external use contains 5% and 10% (by weight) of ethofenamate, which has pronounced anti-inflammatory and analgesic properties. Efenafetat - a non-steroidal anti-inflammatory drug whose action is based on the fact that it indiscriminately suppresses cyclooxygenase type 1 and 2, disrupts the metabolism of arachidonic acid.As a result, the synthesis of prostaglandins is inhibited and the formation of inflammatory mediators is reduced.

    Etophenamate is lipophilic in nature, which causes its good penetration through the skin. Efenafetat penetrates through the skin and is distributed in the affected tissue, in which it reaches therapeutic concentrations. Concerning etofenamate is used mainly in preparations intended for external use.

    Etofenamate maximum concentration in plasma is achieved after a single application Revmonna gel in an amount equivalent to 300 mg etofenamate after 12 - 24 hours after application (21-28 ng / ml). After application on the skin, the relative bioavailability of the drug is within 20%.

    Etopenamate is excreted by the kidneys and through the intestine in the form of its metabolites and their compounds.

    Pharmacokinetics:
    Indications:

    Revmonn gel for topical application 5% and 10% prescribed in the following cases: Closed injuries, bruises, sports injuries, soft tissue injury and Osteoarthritis joints, shoulder joint periarthritis, epicondylitis, lumbago Ankylosing spondylitis, tendinitis, tenosynovitis, peritendinit.

    Contraindications:

    Individual hypersensitivity to one of the components of the drug, to acetylsalicylic acid or other NSAIDs, anamnestic data on the attack of bronchial obstruction, rhinitis; urticaria after taking acetylsalicylic acid or other NSAIDs, violation of the integrity of the skin, children's age (due to inadequate clinical safety data).

    Carefully:

    Erosive-ulcerative lesions of the gastrointestinal tract, severe violations of liver and kidney function, chronic heart failure, elderly age, bronchial asthma.

    Pregnancy and lactation:

    Rheumont gel for external use is contraindicated during pregnancy, since it is established that etofenamate penetrates the placental barrier.

    During the period of application of the medicine Revmont gel for external use, nursing mothers should refuse breastfeeding.

    Dosing and Administration:

    Rheumont gel for topical use is prescribed topically, applied directly to diseased areas, spreading the gel as far as possible over a larger area. A strip of gel with a length of 5-10 cm (1.7-3.3 g of gel with each application,depending on the size of the affected area) is applied to the skin and rubbed in a circular motion 3 or 4 times a day.

    After applying the product, you should thoroughly wash your hands. The course of treatment is from 1 to 2 weeks to several months after consulting a doctor. The maximum duration of the drug without a doctor's consultation is 14 days.

    Side effects:

    In rare cases, reversible allergic reactions in the form of urticaria, dermatitis, individual peeling, erythema, or itching may develop in the area of ​​application of Revmon gel for external use. In this case, stop using the drug and consult a doctor.

    Overdose:Information on the effects of overdose Rheumont gel for external use are absent. With accidental ingestion, it is possible to develop systemic adverse reactions. Treatment: gastric lavage, induction of vomiting, Activated carbon, forced diuresis, symptomatic therapy. Dialysis is not effective due to the high degree of binding of etofenamate to proteins (about 99%).
    Interaction:

    The interaction of rheumont gel for external use with other medications has not been established.

    Special instructions:

    Rheumont gel for external use should not be applied to damaged or eczematous inflammation of the skin, mucous membranes, including the mucous membranes of the eyes. After applying, do not apply an occlusive bandage. With prolonged use and / or application on extensive surfaces, it is possible to develop systemic side effects due to resorptive action. Apply only externally. Impact on the ability to drive vehicles.

    Effect on the ability to drive transp. cf. and fur:The influence of Revmon cream for external use on the ability to drive a vehicle or work with complex mechanisms is not established.
    Form release / dosage:Gel for external use 5%, 10%.
    Packaging:

    By 20 g, 40 g, 50 g and 100 g in aluminum tubes. The tube together with the instruction for use is placed in a cardboard box.

    Storage conditions:

    At a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:5 years from the date of production. Do not use after the expiry date printed on the package.
    Terms of leave from pharmacies:Without recipe
    Registration number:LP-001892
    Date of registration:30.10.2012
    The owner of the registration certificate:Honey Manufacuring GmbHHoney Manufacuring GmbH Germany
    Manufacturer: & nbsp
    Representation: & nbspHoney Manufacuring GmbHHoney Manufacuring GmbH
    Information update date: & nbsp20.10.2015
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