Revmond (Revmonn)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceEfenafetatEfenafetat
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  • Revmond
    spray externally 
    Honey Manufacuring GmbH     Germany
  • Revmond
    gel externally 
    Honey Manufacuring GmbH     Germany
  • Revmond
    emulsion externally 
    Honey Manufacuring GmbH     Germany
  • Revmond
    cream externally 
    Honey Manufacuring GmbH     Germany
    • Dosage form: & nbspcream for external use
    Composition:

    Composition per 1 g:

    Active substance:

    Efenafetat 100.0 mg

    Excipients:

    Benzyl alcohol 15.0 mg; gimetellosis 7.5 mg; citric acid 1.8 mg; glyceryl monostearate 175.0 mg; isopropyl myristate 100.0 mg; macrogol stearate 100 50.0 mg; sodium citrate 7.3 mg; purified water 543.4 mg.

    Description:A homogeneous cream of white color.
    Pharmacotherapeutic group:Non-steroidal anti-inflammatory drug (NSAID).
    ATX: & nbsp

    M.02.A.A.06   Efenafetat

    Pharmacodynamics:

    Rheumont cream for external use contains 10% (by weight) of ethofenamate, which has pronounced anti-inflammatory and analgesic properties. Efenafetat - non-steroidal anti-inflammatory drug, the action of which is based on the fact that it indiscriminately suppresses cyclooxygenase 1 and 2 types, disrupts the metabolism of arachidonic acid. As a result, the synthesis of prostaglandins is inhibited and the formation of inflammatory mediators is reduced.

    Etophenamate is lipophilic in nature, which causes its good penetration through the skin. Concerning etofenamate is used mainly in preparations intended for external use.

    Etophenamate penetrates the skin and is distributed in the affected tissue, in which it reaches therapeutic concentrations. Maximum concentrations of ethofenamate in plasma (19-31 ng / ml) are achieved after a single application of 3 grams of Rheumont cream after 12 - 24 hours after application. The relative bioavailability of the drug does not exceed 20%.

    Etopenamate is excreted by the kidneys, and through the intestine in the form of its metabolites and their compounds.

    Pharmacokinetics:
    Indications:

    Rheumont cream for external use is prescribed in the following cases:

    - Closed injuries, bruises, sports injuries, injuries of soft tissues and joints;

    - Arthrosis, arthrosis of the knee joints (gonarthrosis), osteoarthritis, periarthritis of the shoulder joint, epicondylitis, lumbago;

    - Spondyloarthritis, ankylosing spondylitis, tendonitis, tenosynovitis, and peritendinitis.

    Contraindications:

    - Povppnaya sensitivity to acetylsalicylic acid or other NSAIDs, anamnestic data on an attack of bronchial obstruction, rhinitis, urticaria after taking acetylsalicylic acid or other NSAIDs;

    - Pregnancy, lactation;

    - Children's age (due to lack of clinical data);

    - Violation of the integrity of the skin;

    Carefully:

    Erosive-ulcerative lesions of the gastrointestinal tract, severe violations of liver and kidney function, chronic heart failure, bronchial asthma, elderly age.

    Pregnancy and lactation:

    Revmon cream for external use is contraindicated during pregnancy, since it is established that etofenamate penetrates the placental barrier.

    During the period of application of Revmont cream for external use, lactating mothers should refuse breastfeeding.

    Dosing and Administration:

    Rheumont cream for external use is prescribed by local apply directly to diseased areas, distributing the cream as much as possible over a larger area. A strip of cream 5-10 cm long (1.7-3.3 g each time, depending on the size of the affected area) is applied to the skin and rubbed in a circular motion 3 or 4 times a day. The course of treatment is from 1 to 2 weeks to several months. The maximum duration of the drug without a doctor's consultation is 14 days.

    Side effects:

    In rare cases, reversible allergic reactions in the form of urticaria, dermatitis, peeling, erythema, or itching may develop in the area of ​​application of the Revmont cream for external use. In this case, stop using the drug and consult a doctor.

    Overdose:

    Information on the effects of overdose Revmon cream for external use are absent. With accidental ingestion, it is possible to develop systemic adverse reactions. Treatment: gastric lavage, induction of vomiting, Activated carbon, forced diuresis, symptomatic therapy. Dialysis is ineffective due to the high degree of binding of etofenamate to proteins (about 99%).

    Interaction:

    The interaction of rheumont cream for external use with other medications has not been established.

    Special instructions:

    Revmon cream for external use should not be applied to damaged or eczematous inflammation of the skin, mucous membranes. After applying, do not apply an occlusive bandage. With prolonged use and / or application on extensive surfaces, it is possible to develop systemic side effects due to resorptive action. Apply only externally.

    Effect on the ability to drive transp. cf. and fur:The influence of Revmon cream for external use on the ability to drive a vehicle or work with complex mechanisms is not established.
    Form release / dosage:

    Cream for external use 10%.

    Packaging:By 20, 40, 50 and 100 g in aluminum tubes. The tube together with the instruction for use is placed in a cardboard box.
    Storage conditions:

    At a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiry date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-001386
    Date of registration:20.12.2011
    The owner of the registration certificate:Honey Manufacuring GmbHHoney Manufacuring GmbH Germany
    Manufacturer: & nbsp
    Representation: & nbspHoney Manufacuring GmbHHoney Manufacuring GmbH
    Information update date: & nbsp20.10.2015
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