Sennagood - instructions for use, dose, side effects, contraindications

Excipients: lactose monohydrate - 91.0 mg, croscarmellose sodium 7.2 mg, corn starch 6.0 mg, talc 6.0 mg, silicon colloidal dioxide 5.0 mg, magnesium stearate 2.0 mg, microcrystalline cellulose - to obtain a tablet weighing 200.0 mg.

Description:

Round, biconvex tablets from light brown to dark brown with interspersed.

Pharmacotherapeutic group:laxative herbal remedy

ATX: & nbsp

A.06.A.B Contact laxatives

Pharmacodynamics:

Has a laxative effect, which is due to anthraglikozidami (mainly sennozidami A and B), as well as other glycosides. With the use of glycosides inside the senna pass through the stomach and small intestine in an unchanged form, not absorbed. In the large intestine, the anthroglycosides are digested by intestinal bacteria into pharmacologically active anthrons and anthranoles,which irritate the intestinal receptors of the colon, increase peristalsis and accelerate the emptying of the intestine. Antrons and anthranols interfere with the absorption of water and electrolytes, promote the diffusion of water into the lumen of the intestine. Due to the osmotic effect, loosening of the stool masses and increasing their volume, contributing to the relaxing effect of anthraglycosides.

The laxative effect is manifested after 6-10 hours. With prolonged use of the drug, the intensity of its action may decrease due to a decrease in potassium in the body.

Pharmacokinetics:

Metabolites of anthraglikozid senna are practically not absorbed, mainly they are excreted with feces, as well as with urine. They are also excreted with sweat, they penetrate into breast milk.

Indications:

- Chronic constipation,

- hypo- and atony of the intestine,

- regulation of stool with hemorrhoids, proctitis and anal fissures,

- cleansing of the intestine before the diagnostic and treatment procedures.

Contraindications:

Increased individual sensitivity to the drug components, uterine bleeding, intestinal obstruction, spastic constipation, acute inflammatory bowel disease (Crohn's disease, ulcerative colitis, appendicitis),peritonitis, peptic ulcer of the stomach and duodenum, gastrointestinal bleeding, strangulated hernia, cystitis, pain in the abdomen of an unknown genesis, severe disturbances in the water-electrolyte balance, pregnancy, breastfeeding period, lactase deficiency, lactose intolerance, glucose-galactose malabsorption, children under 12 years.

Carefully:

Diabetes mellitus, liver and / or kidney disease, children age from 12 years.

People on a diet with a low carbohydrate content.

If you have any of these diseases, consult a doctor before taking the drug.

Pregnancy and lactation:

The use of the drug in pregnant women is contraindicated in connection with a higher probability of developing side effects (abdominal pain, diarrhea).

For the duration of treatment with the drug, breastfeeding is recommended to be discontinued, as the components of the drug can penetrate into breast milk and cause frequent stools in the infant.

Dosing and Administration:

Take inside once a day in the evening before going to bed, washing down with water.

Adults and children over 12 years of age - 1-2 tablets; in the absence of effect, the dose is increased to 2-3 tablets per reception. The maximum daily dose is 3 tablets.

It should be used the smallest dose necessary for obtaining soft feces. In the process of selection, the same dose should be taken for several days and, in the absence of effect, gradually increase the dose to 1/2pills. If the maximum dose is not applied within three days of defecation, it is necessary to consult a doctor.

Do not use the drug for more than two weeks.

If it is necessary to use the drug on the recommendation of a doctor, after two weeks of use, you should take a break for two weeks.

Side effects:

From the gastrointestinal tract:

Spastic pains in the abdomen, nausea, vomiting, diarrhea, flatulence, atony of the large intestine, pigmentation of the large intestine (deposition of melanin pigment in the mucosa of the colon).

Allergic reactions: skin itching, erythema, skin rash.

From the genitourinary system:

Yellowish brown or reddish urine staining (due to metabolites excreted by the kidneys, this is not a pathological sign and passes after discontinuation of the drug), proteinuria, hematuria (with prolonged use, especially in high doses).

Metabolic disorders:

Hypovolemia, hypokalemia (with prolonged admission, especially in high doses, with diuretics, corticosteroids and cardiac glycosides), secondary hyperaldosteronism.

Other:

Fatigue, confusion, muscle cramps (with prolonged use).

If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose:

Symptoms: diarrhea, vomiting, abdominal pain, violation of water-electrolyte balance.

Treatment: drug withdrawal, symptomatic therapy, replenishment of fluid and electrolytes (especially potassium) to restore water-electrolyte equilibrium.

Interaction:

With long-term use or use in high doses, the drug enhances the effect of cardiac glycosides and antiarrhythmics, due to a decrease in potassium in the body, disrupts the absorption of antibiotics of the tetracycline series.

With simultaneous use with thiazide diuretics, hormones of the adrenal cortex and licorice preparations, the risk of hypokalemia increases.

Reduces the effectiveness of drugs that are slowly absorbed in the gastrointestinal tract.

Special instructions:

Before using the drug should consult a doctor.

The drug is recommended to be used only if normalization of the stool can not be achieved by changing the diet or using drugs that increase the volume of intestinal contents.

With prolonged use of the drug may develop addiction, in connection with which it is advisable to alternate with other laxatives.

During treatment, acid urine can acquire a tan color, alkaline - a reddish color.

One tablet contains 0.014 XE.

Effect on the ability to drive transp. cf. and fur:

The use of the drug does not affect the ability to perform potentially dangerous activities requiring increased concentration and speed of psychomotor reactions (vehicle management, work with moving mechanisms, dispatcher and operator work).

Form release / dosage:Tablets, 13.5 mg.

Packaging:

For 10 tablets in a contour mesh box made of polyvinylchloride film and aluminum foil printed lacquered.

For 1, 2, 4, 6, 10 and 50 contour mesh packages together with the instruction for use are placed in a pack of cardboard.

Storage conditions:

In a place protected from moisture and light, at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-003755

Date of registration:27.07.2016

Expiration Date:27.07.2021

The owner of the registration certificate:AVVA RUS, OJSC AVVA RUS, OJSC Russia

Manufacturer: & nbsp

AVVA RUS, OJSC Russia

Representation: & nbspAVVA ENG JSC AVVA ENG JSC Russia

Information update date: & nbsp21.08.2016

Illustrated instructions

Instructions

Sennagood (Sennagood)