Protargol (Protargol)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceSilver ProteinSilver Protein
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    • Dosage form: & nbsptablets for solution for topical use
    Composition:

    Composition per 1 tablet:

    Active substance:

    silver proteinate (protargol) - 200.00 mg

    Solvent composition:

    Water for injection - 10 ml.

    Description:

    Tablets are round flat with a risk, from dark brown to black with a bluish tint with an uneven surface color.

    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    R.02.A.A   Antiseptics

    D.08.A.X   Other antiseptics and disinfectants

    D.08.A   Antiseptics and disinfectants

    D.08   Antiseptics and disinfectants

    Pharmacodynamics:

    Upon ingestion, silver proteinate dissociates with the formation of silver ions, which have an astringent, antiseptic and anti-inflammatory effect. Silver ions actively suppress the propagation of pathogens of infection, binding their DNA. The mechanism of action of protargol is based on the fact that silver ions on the damaged mucous membrane precipitate proteins and form a protective film.At the same time, the sensitivity decreases, the blood vessels narrow (this leads to a decrease in edema) and the inflammatory process is suppressed. Silver ions also inhibit the multiplication of various bacteria. It is active against Gram-positive and Gram-negative bacteria: B. cereus, FROM. albicans, E. coli, R. aeruginosa, FROM. aureus, A. niger, S. abony and etc.

    Pharmacokinetics:

    The medicinal preparation Protargol is applied topically, therefore, silver absorption is insignificant, systemic effects and cases of silver poisoning when applied in clinical practice are not revealed.

    Indications:

    Acute respiratory diseases with the phenomena of rhinitis, sinusitis (as part of complex therapy).

    Contraindications:

    Hypersensitivity to the drug components, pregnancy, the period of breastfeeding, age to 18 years (due to the lack of clinical data), atrophic rhinitis.

    Pregnancy and lactation:

    Contraindicated drug pregnant women, as well as women during lactation. If it is necessary to treat a nursing mother with this particular remedy, breast feeding for the period of treatment by Protargolum must be interrupted.

    Dosing and Administration:

    Apply the solution topically.The finished solution should not be stored for more than 30 days in the dark place at a temperature of no higher than 25 ° C.

    Method of preparation of 2% solution:

    1. Place the tablet Protargol 200 mg in a bottle of dark glass.

    2. Open the solvent (water for injections) and pour into the vial.

    3. Close the bottle with a lid-pipette, leave for 20 minutes and then shake well 2-3 times, if the tablet does not dissolve completely, after 5 minutes shake again.

    Bury 3-5 drops in each nostril twice a day (morning and evening) for 5-7 days.

    Before using Protargol for instillation into the nose, the nasal sinus should be completely cleaned and rinsed.

    The main effect of the drug will be manifested only 2-3 days after the first use. If symptoms persist for more than 5-7 days, it is recommended to consult a doctor.

    Use the drug only according to the method of administration and at the doses specified in the instructions for use. If necessary, please consult with your doctor before using the medication.

    Side effects:

    Classification of the incidence of adverse events (WHO): very often more than 1/10, often from 1/100 to 1/10, infrequently from 1/1000 to 1/100, rarely from 1/10000 to 1/1000, very rarely less than 1 / 10000, including individual cases.

    Allergic reactions: rarely allergic reactions (itchy skin, mucous irritation, urticaria), burning sensation and numbness, dry mouth, red eyes, very rarely anaphylactic shock, Quincke's edema, atopic dermatitis.

    With aggravation of any of the side effects indicated in the instructions, the drug should be discontinued. If any of the side effects indicated in the manual are aggravated or you notice any other side effects not listed in the instructions, inform your doctor.

    Overdose:

    So far, no cases of overdose have been reported.

    Interaction:

    Not identified.

    Special instructions:

    Read the instructions for use carefully before using the product. Keep the manual, it may be needed again. If you have any questions, contact your doctor.

    The medicine you are treating is intended for you personally, and it should not be passed on to others, as it can harm them even if you have the same symptoms as you.

    Effect on the ability to drive transp. cf. and fur:

    The drug does not affect the ability to drive vehicles or engage in other potentially hazardousActivities that require increased concentration and speed of psychomotor reactions.

    Form release / dosage:

    Tablets for the preparation of a solution for topical application, 200 mg.

    Packaging:

    1 tablet per contour cell packaging made of polyvinylchloride film and aluminum foil printed lacquered.

    For 1 circuit cell package, 1 polyethylene or polypropylene ampoule with 10 ml of solvent (water for injection, LP-002529 Groteks, Russia), 1 bottle of dark glass with a pipette cap is placed in a pack of cardboard along with instructions for the medical application.

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LP-004659
    Date of registration:25.01.2018
    Expiration Date:25.01.2023
    The owner of the registration certificate:FARMTECHNOLOGIYA, LLC FARMTECHNOLOGIYA, LLC Republic of Belarus
    Manufacturer: & nbsp
    Information update date: & nbsp01.03.2018
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