Regidron (Rehydron)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceDextrose + Potassium chloride + Sodium chloride + Sodium citrateDextrose + Potassium chloride + Sodium chloride + Sodium citrate
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    • Dosage form: & nbspPowder for solution for oral administration
    Composition:

    The drug is a glucose-electrolyte mixture, which includes (per 1 bag): sodium chloride - 3.5 g, potassium chloride - 2.5 g, sodium citrate - 2.9 g, dextrose-10 g. In solution, obtained by dissolving 1 sachet in 1 liter of water, contains the following concentrations of active ingredients:

    Sodium chloride

    59.9 mmol

    Potassium chloride

    33.5 mmol

    Sodium citrate

    9.9 mmol

    Dextrose

    55.5 mmol

    Na +

    89.6 mmol

    K +

    33.5 mmol

    C1-

    93.4 mmol

    Citrate

    9.9 mmol
    Description:

    Crystalline powder of white color.

    The solution obtained after preparation in accordance with the instructions for medical use is colorless, transparent.

    Pharmacotherapeutic group:Rehydrating agent for oral administration.
    ATX: & nbsp

    A.07.C.A   Rehydrate for oral use

    Pharmacodynamics:

    The medicinal preparation of Regidron ® is used to correct the loss of electrolytes and fluid in diarrhea. Dextrose promotes the absorption of electrolytes, which contributes to the correction of metabolic acidosis. Osmolarity of the solution is 282 mosm / l, pH - 8.2.

    Pharmacokinetics:

    The pharmacokinetic properties of water, electrolytes and dextrose that make up the drug are similar to those found in the human body.

    Indications:

    Oral rehydration (replenishment of fluid in the body) and prevention of dehydration in acute diarrhea, accompanied by mild and moderate dehydration. The drug replenishes water and salt reserves.

    Contraindications:

    Hypersensitivity to the components of the drug.

    Severe dehydration.

    Coma (unconscious condition).

    Intestinal obstruction.

    Severe vomiting.

    Diarrhea caused by cholera.

    Glucose-galactose malabsorption.

    Carefully:
    Pregnancy and lactation:

    In recommended doses, Regidron® can be used in pregnancy and lactation.

    Dosing and Administration:

    The contents of one sachet are dissolved in 1 liter of freshly boiled chilled drinking water. The resulting colorless solution is taken orally (orally). If necessary, the solution can be administered through a nasogastric tube (under conditionshospital).

    The prepared solution should be stored in a refrigerator (at a temperature of +2 up to +8 ° С), it should be consumed within 24 hours. In order not to disrupt the effect of the drug, the solution should not be add no other components.

    Before starting treatment, the patient should be weighed to assess the loss of body weight and the degree of dehydration.

    Nutrition or breastfeeding during oral rehydration therapy should not be interrupted, or they should be continued immediately after rehydration. During treatment with the drug it is recommended to avoid eating foods rich in fats and simple carbohydrates (this can aggravate diarrhea).

    To prevent dehydration, the use of Regiodron® should be started as soon as diarrhea has started. Usually the drug should be used no more than 3-4 days, treatment stops with the end of diarrhea. If nausea or vomiting occurs, it is advisable to take the solution in chilled form in small portions (eg, tea spoons).

    Replenishment of liquid

    To replenish the Regidron® fluid take for the first 6-10 hours in an amount that is doubled

    exceeds the loss of body weight caused by diarrhea. For example, if the body weight loss is 400 g, the volume of the Regidron® solution is 800 ml. During this phase, the use of other liquids is not required. Take food in the first 4 hours of replenishing the fluid is not recommended. When large amounts are taken, vomiting may occur.

    Prevention of dehydration

    If diarrhea continues, after correcting the dehydration, it is advisable to take Regidron® and water for 24 hours as follows:

    Weight bodies (kg)

    General information quantity the required liquid (l)

    Regidro

    (ml)

    Water

    (ml)

    Other

    fluids

    (ml)

    40-49

    2,10

    900

    540

    660

    50-59

    2,30

    1000

    600

    700

    60-69

    2,50

    1100

    660

    740

    70-79

    2,70

    1200

    720

    780

    80-89

    3,20

    1400

    800

    1000

    90-99

    3,60

    1500

    900

    1200

    100 and more

    4,00

    1700

    1000

    1300
    Side effects:

    In patients with normal renal function, the risk of hypernatremia (elevated sodium in the blood) or excess water intake is low. If you receive too quickly, you may experience vomiting.

    Overdose:

    When introducing a large volume or a highly concentrated solution of Regidron® (in violation of the rules for the preparation of the solution), hypernatremia may occur (an increase in the sodium content in the blood). Symptoms of hypernatremia include weakness, neuromuscular excitement, drowsiness, confusion, coma, sometimes even stopping breathing.In patients with impaired renal function, hyperkalemia (increased potassium content in the blood) may occur, manifested by a heart rhythm disorder, weakness.

    If symptoms of an overdose occur, consult a doctor. Correction of water-electrolyte balance should be carried out on the basis of laboratory data.

    Interaction:

    Not studied. The solution of the preparation has a slightly alkaline reaction, therefore it can influence the drugs, the absorption of which depends on the pH of the contents of the intestine. Diarrhea itself can alter the absorption of many drugs that are absorbed in the small or large intestine, or drugs in the metabolism of which has intestinal hepatic circulation.

    Special instructions:
    Children should use other solutions with a lower sodium content and osmolarity.

    Given the composition of the drug, caution should be exercised in patients with diabetes mellitus, impaired liver or kidney function, as well as in patients who follow a diet low in salt (sodium and / or potassium).

    In patients with diabetes mellitus,renal insufficiency and some other chronic diseases, diarrhea can cause a significant disturbance in maintaining a balance of fluid or glucose. In this regard, the treatment of diarrhea in such patients may require laboratory monitoring and hospitalization.

    If the patient's need for additional electrolyte administration is not confirmed by laboratory tests, the recommended dose of the drug should not be exceeded.

    Severe dehydration (loss of body weight> 10%, discontinuation of urine output) should be treated with intravenous preparations for rehydration, after which the use of Regidron® solution is permitted.

    If intravenous administration is necessary, or with severe dehydration or severe vomiting, with a decrease or discontinuation of urine output, use of Regidron® should be used with caution.

    When vomiting, wait for 10 minutes after the end of a fit of vomiting and allow to drink the solution slowly, in small sips.

    The patient should consult a doctor if, during the use of Regidron®, the following situations occur:

    - there is a delayed speech, irritability, rapid fatigue, drowsiness, stupor;

    - the temperature rises above 39 ° C;

    - bloody stools;

    - incessant vomiting;

    - Diarrhea lasts more than 2 days;

    - severe pain in the abdomen.

    The use of the Regidron® solution to compensate for salt loss in diarrhea that develops with cholera and a number of other serious intestinal infections may not be sufficient.

    Persons with renal insufficiency or a diet low in potassium should take into account that the preparation contains potassium.

    Effect on the ability to drive transp. cf. and fur:

    Does not affect the ability to drive vehicles and engage in other potentially dangerous activities that require increased concentration and speed of psychomotor reactions.

    Form release / dosage:

    Powder for solution for oral administration.

    Packaging:

    For 18.9 grams of powder in bags of polyethylene / aluminum / Surlin® - laminate.

    For 4 or 20 bags in a cardboard pack together with instructions for use.

    Storage conditions:

    At a temperature of 15 to 25 ° C.

    After dilution, the solution is stored in the refrigerator for 24 hours. Keep out of the reach of children!

    Shelf life:

    3 years.

    Do not use after the expiry date printed on the package!

    Terms of leave from pharmacies:Without recipe
    Registration number:П N014770 / 01
    Date of registration:18.03.2010 / 29.09.2015
    Expiration Date:Unlimited
    The owner of the registration certificate:Orion Corporation Orion Pharma Orion Corporation Orion Pharma Finland
    Manufacturer: & nbsp
    Representation: & nbspFARMAKOR PRODUCTION LLC FARMAKOR PRODUCTION LLC Russia
    Information update date: & nbsp01.12.2016
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