Regulax Picosulfate - instructions for use, dose, side effects, contraindications

Laxative. The active form of the preparation, formed by hydrolysis under the influence of intestinal microorganisms, directly excites the nerve structures of the intestinal wall, as a result of which the movement of intestinal contents accelerates, the absorption of electrolytes and water decreases.The action occurs 10-12 hours after admission.

Pharmacokinetics:After oral administration, it is not absorbed from the gastrointestinal tract and is not subjected to hepatic-intestinal circulation.

Indications:

Atonic constipation. Regulation of the stool (hemorrhoids, proctitis, anus fractures). Preparation for surgical operations, instrumental and roentgenological studies.

Contraindications:

Hypersensitivity, intestinal obstruction, strangulated hernia, acute inflammatory diseases of the abdominal cavity, peritonitis, abdominal pain (unclear genesis), bleeding from the gastrointestinal tract, metrorrhagia, cystitis, severe dehydration, spastic constipation, children's age (up to 4 years), pregnancy I trimester.

Carefully:With caution-lactation period

Pregnancy and lactation:

Contraindicated in the first trimester of pregnancy. Multiple drug intake during the II and III trimesters should be performed only after a thorough assessment of the need and risks, since there is insufficient information about the use of the drug during pregnancy.

Dosing and Administration:

Inside, before bed.Depending on the effect obtained, the dose in subsequent administration is increased or decreased. Adults: the initial dose - 13 drops, with persistent constipation - up to 26 drops. For children older than 4 years, the initial dose is 5-8 drops. A course of treatment 1 days.

Side effects:

Diarrhea, abdominal pain, bloating, dehydration, water-electrolyte imbalance, weakness, convulsions, lowering of blood pressure.

Overdose:

Symptoms: see the "Side effect" section. In addition, with chronic overdose it is possible to develop ischemia of the mucous membrane of the colon, secondary hyperaldosteronism, urolithiasis, and damage to the renal tubules.

Treatment: gastric lavage, correction of water-electrolyte balance disorders, antispasmodics.

Interaction:

Perhaps increased sensitivity to cardiac glycosides. Glucocorticosteroids, diuretics increase the risk of electrolyte disorders. Antibiotics of a wide spectrum of action reduce a laxative effect.

Special instructions:

Do not take without medical supervision for more than 7 days. Long-term administration often leads to increased intestinal fixation. Children should be used only in consultation with a doctor.

Guidelines for patients with diabetes mellitus:

Suitable for diabetics; contains sugar substitutes; 1 ml resp. 0,03 ХЕ

Effect on the ability to drive transp. cf. and fur:not described

Form release / dosage:

Drops for oral administration 7.5 mg / ml. 10 ml, 20 ml and 50 ml of the drug are placed in bottles of brown glass with a stopper and a screw cap of white color. The bottle together with the instruction for use is placed in a cardboard box.

Packaging:bottle-dropper dark glass (1) -package cardboard

Storage conditions:

At a temperature of 15 ° C to 25 ° C, out of reach of children.

Shelf life:

5 years.

Shelf life after opening the bottle is 6 months.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:П N011499 / 01

Date of registration:15.12.2008

The owner of the registration certificate:Crevel Moiselbach GmbHCrevel Moiselbach GmbH Germany

Manufacturer: & nbsp

KREWEL MEUSELBACH, GmbH Germany

Representation: & nbspCrevel Moiselbach GmbH Crevel Moiselbach GmbH

Information update date: & nbsp19.02.2009

Illustrated instructions

Instructions

Regulax® Picosulphate (Regulax® Picosulfate)