Slabilen - instructions for use, doses, side effects, contraindications

Excipients: methylparahydroxybenzoate sodium in terms of anhydrous substance 2.06 mg, sorbitol (sorbitol food) - 375.0 mg, hydrochloric acid 1M solution - 0.01 ml, purified water - up to 1 ml.

Description:transparent slightly viscous colorless or slightly colored liquid

Pharmacotherapeutic group:laxative

ATX: & nbsp

A.06.A.B.08 Sodium picosulphate

Pharmacodynamics:

Sodium picosulfate is a laxative. Under the action of intestinal microorganisms, it hydrolyzes with the formation of an active form, which causes excitation of the receptors of the mucous membrane of the large intestine and the intensification of its peristalsis.The action occurs 10-12 hours after admission.

Pharmacokinetics:

After oral administration, it is not absorbed from the gastrointestinal tract and is not subjected to hepatic-intestinal circulation.

Indications:

Constipation due to hypotension and flaccid peristalsis of the colon. Regulation of stool with hemorrhoids, proctitis, cracks anus. Preparation for surgical operations, instrumental and roentgenological studies.

Contraindications:

Hypersensitivity to any of the components of the drug, intestinal obstruction, strangulated hernia, acute inflammatory diseases of the abdominal cavity, peritonitis, abdominal pain (unclear genesis), bleeding from the gastrointestinal tract, metrorrhagia, cystitis, severe dehydration, spastic constipation, childhood ( up to 4 years), pregnancy (I trimester).

Carefully:II and III trimesters of pregnancy, lactation.

Pregnancy and lactation:

There are no data on reliable and well-controlled studies in pregnant women. Long-term experience of use has not revealed a negative effect of sodium picosulfate on pregnancy. The use of sodium picosulfate in the first trimester of pregnancy is contraindicated.In the II and III trimesters of pregnancy (as well as with the use of other laxatives), the drug is only possible for the doctor's prescription.

The active metabolite and its glucuronides are not excreted in breast milk. Thus, the drug can be used during breastfeeding.

Dosing and Administration:

Inside with a little water, before going to sleep.

Adults: the initial dose is 10-20 drops, with persistent constipation - up to 30 drops.

For children older than 4 years, the initial dose is 5-8 drops.

Depending on the effect obtained, the dose in subsequent administration is increased or decreased. The maximum daily intake for adults is 30 drops; for children - 15 drops.

Side effects:

Diarrhea, abdominal pain, dehydration, water-electrolyte balance disorders, weakness, convulsions, lowering of blood pressure.

Overdose:

Symptoms: diarrhea, dehydration, lowering of arterial pressure, violations of water-electrolyte balance, convulsions. In addition, with chronic overdose it is possible to develop ischemia of the mucous membrane of the colon, secondary hyperaldosteronism, urolithiasis, and damage to the renal tubules. Treatment: gastric lavage, correction of water-electrolyte balance disorders, antispasmodics.

Interaction:

Perhaps increased sensitivity to cardiac glycosides. Glucocorticosteroids, diuretics increase the risk of electrolyte disorders.

Antimicrobials of a wide spectrum of action reduce the effectiveness of sodium picosulphate.

Special instructions:

Do not use daily without medical supervision for more than 10 days. Children should only be used as directed by a doctor.

It has no taste, so children can be added to food.

Effect on the ability to drive transp. cf. and fur:Sodium picosulfate does not affect the ability to drive a car and perform work that requires a high rate of psychomotor reactions.

Form release / dosage:

Drops for oral administration 7.5 mg / ml. For 15 ml in bottles of lightproof glass with a stopper dropper. For 30 ml in bottles of light-protective glass complete with a dropper. Each bottle, together with the instructions for use, is placed in a pack of cardboard.

Packaging:bottle-dropper light-protective glass (1) -package cardboard
bottles of light-protective glass (1) / complete with lids-droppers / -tacks of cardboard

Storage conditions:

In a place protected from light and inaccessible to children at a temperature not lower than 8 ° С.

Shelf life:

3 years. Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:P N002911 / 01

Date of registration:15.08.2008

The owner of the registration certificate:LENS-PHARM, LLC LENS-PHARM, LLC Russia

Manufacturer: & nbsp

LENS-PHARM, LLC Russia

Information update date: & nbsp10.11.2014

Illustrated instructions

Instructions

Slabilen (Slabilen)