Active substanceSodium picosulphateSodium picosulphate
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  • Dosage form: & nbspdrops for oral administration
    Composition:

    In 1 ml (15 drops) is contained as an active substance:

    Sodium picosulphate 7.5 mg

    Excipients: sorbitol, propylene glycol, water for injection.

    Description:

    transparent, slightly viscous colorless or slightly colored liquid.

    Pharmacotherapeutic group:Laxative
    ATX: & nbsp

    A.06.A.B.08   Sodium picosulphate

    Pharmacodynamics:

    Laxative. The active form of the preparation, formed by hydrolysis under the influence of intestinal microorganisms, directly excites the nerve structures of the intestinal wall, as a result of which the movement of intestinal contents accelerates, the absorption of electrolytes and water decreases.The action occurs 10-12 hours after admission.

    Pharmacokinetics:

    After oral administration, it is not absorbed from the gastrointestinal tract and is not subjected to hepatic-intestinal circulation.

    Indications:

    Atonic constipation. Regulation of the stool (hemorrhoids, proctitis, anus fractures). Preparation for surgical operations, instrumental and roentgenological studies.

    Contraindications:

    Hypersensitivity, intestinal obstruction, strangulated hernia, acute inflammatory diseases of the abdominal cavity, peritonitis, abdominal pain (unclear genesis), bleeding from the gastrointestinal tract, metrorrhagia, cystitis, severe dehydration, spastic constipation, children's age (up to 4 years), pregnancy (I trimester).

    Carefully:lactation period.
    Pregnancy and lactation:contraindicated
    Dosing and Administration:

    Inside, before bed. Adults: the initial dose - 10 drops, with persistent constipation - up to 30 drops. For children older than 4 years, the initial dose is 5-8 drops. Depending on the effect obtained, the dose in subsequent administration is increased or decreased.

    Side effects:

    Diarrhea, abdominal pain, dehydration, water-electrolyte balance disorders, weakness, convulsions, lowering of blood pressure.

    Overdose:

    Symptoms: see the "Side effect" section.In addition, with chronic overdose it is possible to develop ischemia of the mucous membrane of the colon, secondary hyperaldosteronism, urolithiasis, and damage to the renal tubules.

    Treatment: gastric lavage, correction of water-electrolyte balance disorders, antispasmodics.

    Interaction:

    Perhaps increased sensitivity to cardiac glycosides. Glucocorticosteroids, diuretics increase the risk of electrolyte disorders. Antibiotics of a wide spectrum of action reduce a laxative effect.

    Special instructions:

    Do not use daily without medical supervision for more than 10 days. Children should only be used as directed by a doctor.

    It has no taste, so children can be added to food.
    Effect on the ability to drive transp. cf. and fur:not described
    Form release / dosage:

    Drops for oral administration 7.5 mg / ml. 15 ml each bottles - droppers of dark glass. 10 ml each Vials of polyethylene or other polymeric with stoppers - droppers. Each bottle with instructions for application is placed in a pack of cardboard.

    Packaging:
    Storage conditions:

    In the dark place at a temperature of no higher than 20 ° C.

    Shelf life:2 years.Do not use after the expiration date.
    Terms of leave from pharmacies:Without recipe
    Registration number:P N002754 / 01-2003
    Date of registration:26.05.2009
    The owner of the registration certificate:SYNTHESIS, OJSC SYNTHESIS, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp26.05.2009
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