Salicylic acid can increase skin permeability for other medicinal products.
means for topical administration and thereby enhance their absorption. Sucked up
salicylic acid can increase the side effects of methotrexate and oral hypoglycemic drugs, derivatives of sulfonylurea. The solution is pharmaceutically incompatible with resorcinol (forms melting mixtures) and zinc oxide (insoluble zinc salicylate).