Timogen® (Thymogen®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceAlpha-glutamyl-tryptophanAlpha-glutamyl-tryptophan
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  • Timogen®
    spray nazal. 
    CITOMED MB NPK, CJSC     Russia
  • Timogen®
    cream externally 
    CITOMED MB NPK, CJSC     Russia
  • Timogen®
    solution w / m 
    CITOMED MB NPK, CJSC     Russia
    • Dosage form: & nbspsolution for intramuscular injection
    Composition:

    1 ml of the preparation contains: active substance: alpha-glutamyl-tryptophan sodium (Timogen® sodium) 100 μg (in terms of alpha-glutamyl-tryptophan), Excipients: sodium chloride 9000 mcg, water for injection up to 1 ml.

    Description:Colorless transparent solution odorless.
    Pharmacotherapeutic group:Immunostimulating agent
    ATX: & nbsp

    L.03.A.A   Colony-stimulating factors

    Pharmacodynamics:Has a regulatory effect on the reactions cellular, humoral immunity and nonspecific resistance of the body. Stimulates regeneration processes in case of their inhibition. Improves the course of the processes of cellular metabolism. Enhances the expression of differentiating receptors on lymphocytes, normalizes the number of T-helpers, cytotoxic T-lymphocytes and their ratio in patients with various immunodeficiency states.
    Pharmacokinetics:The drug quickly enters the systemic bloodstream after its parenteral administration. Alpha-glutamyl-tryptophan sodium under the action of peptidases is split into L-glutamic acid and L- tryptophan, which are used by the body in peptide synthesis.
    Indications:

    In the complex therapy of acute and chronic viral and bacterial diseases, accompanied by a decrease in immunity:

    - viral hepatitis;

    - acute and chronic nonspecific lung diseases (CHDL): chronic bronchitis, acute and chronic pneumonia;

    - Diseases of the skin and subcutaneous tissue (pyoderma, furunculosis, erysipelas);

    - in the complex therapy of severe diffuse forms of atopic dermatitis;

    - in complex therapy of severe mechanical, chemical, radiation and thermal injuries (burn disease);

    - complex treatment of wound and surgical infection, including purulent-septic complications in the postoperative period;

    - in the period of preoperative preparation with planned surgical operations to prevent infectious complications and stimulate regeneration processes.

    - after radiation therapy, chemotherapy, as well as long-term antibiotic therapy in large doses.

    Contraindications:Hypersensitivity to the components of the drug. Children up to 6 months.
    Carefully:Application features a drug for children and adults with chronic diseases is not.
    Pregnancy and lactation:

    For safety reasons, due to insufficient data, the purpose of the drug during pregnancy and the period of breastfeeding is possible only if the intended benefit to the mother exceeds the potential risk to the fetus or the baby.

    Dosing and Administration:

    Intramuscularly once a day.

    Adults and children from 14 years old have 100 μg (300-1000 μg per course), children from 6 months to 1 year - 10 μg, from 1 to 3 years - 10-20 μg, from 4 to 6 years - 20-30 mcg, from 7 to 14 years - 50 mcg. The duration of the course of treatment is from 3 to 10 days. Conducting a second course is possible not earlier than in 1 month. During the year, 4 courses are possible.

    Precautions for use:

    Not required.

    Indication of the specificity of the action of the drug at the first admission or when it is withdrawn, the actions of the doctor and the patient:

    The drug does not have any special effects at the first reception and upon its cancellation.


    Side effects:

    Allergic reactions.

    Overdose:

    Symptoms of overdose are not described.

    Interaction:

    Not found.

    Effect on the ability to drive transp. cf. and fur:

    The drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

    Form release / dosage:Solution for intramuscular injection 100 μg / ml.
    Packaging:

    Solution for intramuscular injection of 100 mcg / ml per 1 ml in ampoules of colorless glass with an impression and a ring of fracture, or with an impression, a notch and a dot. 5 ampoules per circuit cell packaging made of polyvinylchloride film and aluminum foil or without foil. 1 or 2 contoured cell packs (with foil or without foil) together with instructions for use in a pack of cardboard. 5 ampoules together with instructions for use in a pack of cardboard.

    Storage conditions:

    At a temperature of 0 ° C to 10 ° C.

    Indication of the need for storage of medicinal products in places inaccessible to children:

    Keep out of the reach of children.

    Shelf life:

    3 years. Do not use after the expiration date printed on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:LS-002304
    Date of registration:13.09.2011
    The owner of the registration certificate:CITOMED MB NPK, CJSC CITOMED MB NPK, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp25.08.2015
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