The drug exhibits cerebroprotective, antihypoxic, antioxidant and metabolic action, promotes synthesis in gamma-aminobutyric acid (GABA) and serotonin neurons, and limits the necrosis zone. Pharmacological activity of the drug is determined by the combined effect of the components on the production of ATP in the mitochondria. The substrate of the Krebs cycle succinic acid activates succinate dehydrogenase, supports the activity of the fastest succinate oxidase pathway for the formation of macroerges. Due to the regulatory effect of succinic acid, the formation of free radicals decreases, the activity of antioxidant defense enzymes and the energy potential of the cell are restored.It activates the oxidation-reduction enzymes of the respiratory chain of the mitochondria, promotes the utilization of glucose and fatty acids, stimulates the synthesis of protein and nucleic acids, the resynthesis of macroerges even under conditions of severe ischemia and hypoxia. succinic acid has a pronounced antitoxic effect, providing the necessary energy support to the systems of detoxification and elimination. The predecessor of ATP-riboxin has antihypoxic, metabolic and anabolic effects. It facilitates the utilization of carbohydrates by the cell, pyruvic acid, improves oxidative processes due to the activation of xanthine dehydrogenase and the enzymes of the Krebs cycle; the effect is manifested even with a lower concentration of oxygen in the blood. Riboxin improves the energy balance of cells, activates tissue regeneration, reduces platelet aggregation. Riboflavin normalizes the metabolic processes of mitochondria during hypoxia and increased demand for ATP, interacting with adenosine triphosphoric acid and forming a flavinadenine mononucleotide and flavinadenine dinucleotide - coenzymes of flavinproteins providing the activity of succinate-oxidase complex and cytochro-C-reductase.It promotes the activation of carbohydrate, protein and fat metabolism, regulates oxidation-reduction processes, participates in the synthesis of hemoglobin, in the maintenance of normal visual function of the eye. Nicotinamide is a coenzyme of NAD- and NADP-dependent dehydrogenases of mitochondria, providing oxidation-reduction and synthetic processes due to hydrogen transfer. He takes an active part in carbohydrate, protein and fat metabolism, tissue respiration. Nicotinamide stimulates the utilization of glucose, improves microcirculation, has an antitoxic and weak anticoagulant effect; participates in the regulation of higher nervous activity, reducing the deficiency of tryptophan, a precursor of the neurotransmitter serotonin. By facilitating the synthesis of serotonin in the central nervous system, nicotinamide reduces insomnia, depression, depression, anxiety, nervousness, delirium, hallucinations, helps concentration of attention.
The drug improves cerebral blood flow, metabolic processes in the central nervous system, eliminates reflex disorders, sensitivity disorders, improves the intellectual and mnestic functions of the brain.