Active substancePovidone-iodinePovidone-iodine
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  • Dosage form: & nbspsolution for local and external use
    Composition:

    Povidone-iodine 30/06 105 g; solution of sodium phosphate trisubstituted saturated to pH 2.5-3.5, water purified to 1 liter.

    Description:

    Film-forming dark brown liquid without a smell or with a weak specific smell, is mixed with water in all proportions.

    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.G.02   Povidone-iodine

    Pharmacodynamics:

    Antiseptic, is a 10% solution of iodine-polyvinylpyrrolidone (complex of iodine with polyvinylpyrrolidone). Contains 1% active iodine.

    The drug has a wide range of antimicrobial effects. Has antiseptic, disinfectant, antifungal and antiprotozoal effect. It blocks amino groups of cellular proteins.

    Polyvinylpyrrolidone-iodine refers to iodophors, in which iodine is in a bound state, and is gradually and evenly released upon contact with the skin and mucous membranes, having a bactericidal effect on microorganisms.

    Due to the sorption properties of povidone, Aquazan partially binds the toxic products of microbial and tissue decay and exerts a dehydrating effect on the tissues.

    At the site of application of the drug remains a thin colored layer, which is maintained until all the active iodine is released from the complex, after which the action of the drug ceases.

    The preparation does not possess a local irritant effect, since iodine in it is in the form of a complex.

    Indications:

    - Treatment and prevention of infection of wounds, abrasions, burns, trophic ulcers, pressure sores;

    - treatment of pyoderma, acne, infectious dermatitis, dermatomycosis, skin reaction after the bite of insects;

    - treatment of mucous membranes, including for the local treatment of gynecological diseases and obstetric practice;

    - for rinsing the mouth and throat with infections of the nasopharynx and diseases of the oral cavity (stomatitis, periodontitis, etc.);

    - skin treatment before and after operations or manipulations related to skin disorders (injections, punctures, biopsy, collection of blood, catheterization, etc.);

    - hygienic treatment of patients;

    - pre- and postoperative treatment of the hands of the surgeon, medical personnel; hygienic treatment of hands in the care of infectious patients; treatment of tools and items of patient care.

    Contraindications:

    - Hypersensitivity to iodine;

    - thyrotoxicosis;

    - adenoma of the thyroid gland;

    - herpetiform dermatitis of Dühring;

    - simultaneous application of radioactive iodine;

    - the period of newborns, especially in premature infants.

    Carefully:In chronic kidney failure, pregnancy (II-III trimester), during lactation.
    Dosing and Administration:

    The drug is applied topically and topically.Depending on the field of application Aquazan is used both without dilution, and in the form of aqueous solutions in a dilution of 1: 2, 1:10 or 1: 100.

    To handle small wounds, abrasions, burns, etc. Aquazane is used in undiluted form by lubricating the surface or in the form of a wet lining.

    For disinfection of healthy skin areas before puncture, blood sampling, biopsy, etc. apply the undiluted drug for 1-2 minutes.

    For disinfection of the skin and mucous membranes before surgery and invasive interventions (including in obstetric and gynecological practice), the operating field is treated with an undiluted preparation twice with an exposure of 2 minutes.

    To treat the hands of surgical personnel, 5 ml of undiluted preparation is rubbed with palms up to the elbow for 5 minutes, then carefully rinsed. The procedure is repeated twice.

    To treat infections of the skin and mucous membranes, the drug is used undiluted by surface treatment for 1-2 minutes.

    Rinse mouth and throat produce undiluted or diluted (5 ml per 1/2 glass of water) with the drug.

    For hygienic treatment of a patient before surgery, during the so-called "disinfecting bathing",Aquazane is used in a dilution of 1: 100 by wiping the patient with a sponge moistened with a solution.

    For the prevention and treatment of complications after invasive manipulation, in the treatment of purulent wounds the drug is used without dilution or in dilution 1:2, applying to the surface by lubrication or in the form of a wet lining.

    When treating burns, depending on the condition of the wound, Aquazan is used without dilution or in a 1:10 dilution. The dressing material is impregnated with an undiluted preparation.

    To treat bacterial or fungal dermatitis, Aquasan is used in a 1:10 dilution.

    At home, to treat the skin on its healthy areas or when handling small wounds, scratches, burns, bacterial and fungal skin lesions Aquasan is recommended to be used undiluted.

    Aquazan should be diluted immediately before use. The diluted Aquasan solution in a ratio of 1: 2 and 1:10 store no more than 10 days, in a ratio of 1: 100 no more than 3 days.

    Side effects:

    Allergic reactions, local reactions (itching, hyperemia in place of application).

    Overdose:

    Perhaps increased side effects, including allergic reactions.

    Interaction:Pharmaceutically incompatible with disinfectants containing mercury; oxidizers, reducing agents, alkalis and acids.
    Special instructions:

    Avoid contact with the eyes.

    Light and temperature above 40 ° C accelerates the decrease in drug activity.

    The drug solution should have a dark brown color.

    Discoloration of the solution indicates the destruction of the polyvinylpyrrolidone-iodine complex and a decrease in the effectiveness of the preparation.

    In the presence of blood, the bactericidal action of the drug may decrease.

    Form release / dosage:Solution for local and external use, 10%.
    Packaging:

    For 10 ml in bottles of orange glass with a screw neck, sealed with plastic lids with a brush rod.

    For 50 ml, 100 ml, 500 ml and 1000 ml of the drug in orange glass vials with a screw neck, sealed with plastic caps and caps screwed on plastic. For 250 ml in bottles of orange glass, capped with screw polymer caps. 10 ml, 15 ml, 25 ml, 100 ml, 250 ml, 330 ml, 500 ml, 1000 ml and 4500 ml into polyethylene terephthalate bottles, capped with screw-type polyethylene caps with perforations.Vials can be equipped with medical attachments (nebulizers / dispensers) for medicines, non-sterile with protective caps and without them.

    Each bottle of 10 ml, 15 ml, 25 ml, 50 ml and 100 ml, together with the instruction for use, is placed in a pack of cardboard.

    Packs are placed in corrugated boxes or packed in shrink film.

    Vials, together with an equal number of instructions for use, are packed in cartons or packed in shrink film: 250 ml each - 20 pcs., 330 ml -16 pcs., 500 ml - 12 pcs., 1000 ml -8 pcs., 4500 pcs. ml - 4 pcs. (for hospitals).

    Labels are applied to vials, packs and group packages. The text of the instructions for use on the pack is allowed.

    Storage conditions:In a place protected from light and inaccessible to children at a temperature not above 30 ° ะก.
    Shelf life:3 years.
    Do not use after expiry date.
    Terms of leave from pharmacies:Without recipe
    Registration number:P N003063 / 01
    Date of registration:01.12.2009 / 01.02.2017
    Expiration Date:Unlimited
    The owner of the registration certificate:IODINE TECHNOLOGIES AND MARKETING, LTD. IODINE TECHNOLOGIES AND MARKETING, LTD. Russia
    Manufacturer: & nbsp
    Representation: & nbspIODINE TECHNOLOGIES AND MARKETING, LTD.IODINE TECHNOLOGIES AND MARKETING, LTD.
    Information update date: & nbsp24.06.2017
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