Single dose for adults and adolescents over 15 years is 2-5 ml (intravenously or intramuscularly), daily dose - up to 10 ml. Intravenous injection of a single dose, exceeding 2 ml, is possible only after careful specification of the indications.
For children and infants, the daily dose is set taking into account the body weight (see table).
Table.
| Body weight / age | Solution for injection, intravenous | Solution for injection, intramuscular injection |
| Breastfed babies 5-8 kg; 3-11 months. | Intravenous administration is contraindicated | 0.1-0.2 ml |
| Children 9-15 kg; 1 -2 years | 0.1-0.2 ml | 0.2-0.3 ml |
| Children 16-23 kg; 3-4 years | 0.2-0.3 ml | 0.3-0.4 ml |
| Children 24-30 kg; 5-7 years | 0.3-0.4 ml | 0.4-0.5 ml |
| Children 31 -45 kg; 8-12 years old | 0.5-0.6 ml | 0.6-0.7 ml |
| Children 46-53 kg; 12-15 years old | 0.8-1.0 ml | 0.8-1.0 ml |
Intravenous administration of the drug should be carried out slowly (1 ml for at least 1 min), in the position of the patient lying down and under the control of blood pressure, the frequency of cardiac contractions and breathing. The injection solution must have a body temperature.
The solution is incompatible in one syringe with any other medicines. Side effect
In therapeutic doses, the drug is usually well tolerated. Sometimes allergic reactions are possible (skin rash, itching, very rarely anaphylactic shock, Stevens-Johnson and Lyell syndromes). In rare cases - a burning sensation in the epigastric region, dry mouth, headache.
Possible dizziness, lowering blood pressure, tachycardia, cyanosis. With prolonged admission - cases of hemopoiesis (thrombocytopenia, granulocytopenia, agranulocytosis, hemorrhage). With propensity to bronchospasm may provoke an attack.