Clinical and pharmacological group: & nbsp

Other non-narcotic analgesics, including non-steroidal and other anti-inflammatory drugs

Included in the formulation
  • Cleanness Grass
    powderraw materials. externally 
    LEK S +, LLC     Russia
  • Cleanness Grass
    raw materials. externally 
  • Cleanness Grass
    powderraw materials. externally 
    St.-MEDIFARM, CJSC     Russia
  • Cleanness Grass
    raw materials. externally 
  • Cleanness Grass
    raw materials. externally 
    APEX, LTD.     Russia
  • Cleanness Grass
    raw materials. externally 
    LEK S +, LLC     Russia
  • Cleanness Grass
    raw materials. externally 
    FITOFARM PKF, LLC     Russia
  • Cleanness Grass
    powderraw materials. externally 
  • Cleanness Grass
    raw materials. externally 
  • Cleanness Grass
    raw materials. externally 
    St.-MEDIFARM, CJSC     Russia
  • Cleanness Grass
    powderraw materials. externally 
  • Cleanness Grass
    raw materials. externally 
  • АТХ:

    A.01.A.B.11   Other

    Pharmacodynamics:

    Means of plant origin. The complex of biologically active substances, primarily alkaloids, provides a wide range of pharmacological activity of celandine grass. The main types of action include anti-inflammatory, spasmolytic, choleretic and some analgesic effect.

    Fresh celandine juice has a virusostatic effect.

    Spasmolytic activity of celandine grass is due to the action of the basic chelidonine alkaloid, in addition, chelidonine has morphine-like properties. Homochelidonin, by contrast, has an exciting effect on the central nervous system, can cause seizures, and has local anesthetic activity. The alkaloid protopin reduces the reactivity of the autonomic nervous system and, unlike chelidonin, increases the tone of smooth muscle. The amount of alkaloids of sanguinarine and cheleretrine (sanguirithrin) has a distinct anticholinesterase effect. Sangviritrin acts bactericides on gram-positive and gram-negative bacteria, as well as yeast-like fungi and trichomonads.

    Pharmacokinetics:

    Not described.

    Indications:

    For external use: poorly healing wounds, skin tuberculosis, eczema, warts, calluses, lichen. For oral administration: liver disease, gall bladder, gout.

    I.A15-A19.A18   Tuberculosis of other organs

    II.D10-D36.D23   Other benign neoplasms of the skin

    XI.K80-K87.K80   Gallstone disease [cholelithiasis]

    XI.K80-K87.K81   Cholecystitis

    XI.K80-K87.K83.0   Cholangitis

    XII.L20-L30.L20.8   Other atopic dermatitis

    XII.L20-L30.L28.0   Simple chronic lichen

    XII.L40-L45.L43   Lichen red flat

    XIII.M05-M14.M10   Gout

    XIX.T79.T79.3   Post-traumatic wound infection, not elsewhere classified

    Contraindications:

    For oral administration: epilepsy, bronchial asthma, stenocardia, during pregnancy and lactation.

    Carefully:

    If ingested in case of an overdose, paralysis of the respiratory center is possible.

    Pregnancy and lactation:

    Category of recommendations for FDA is not defined. Qualitative and well-controlled studies on humans and animals have not been conducted. There is no information on the penetration into breast milk. Do not apply!

    Dosing and Administration:

    Outer in the form of baths (1-2 glasses of infusion on the bath for adults), lotions, washings.

    Preparation of the infusion: 3 g (2 teaspoons) celandine herbs are placed in enamel ware, pour 200 ml (1 glass) of hot boiled water, cover with a lid and insist on a boiling water bath for 15 minutes, then cool at room temperature for 45 minutes, filter, remaining raw materials squeeze out. The volume of the infusion obtained is adjusted to 200 ml with boiled water.

    2 filter packs (3 g) are placed in a glass or enamel ware, pour 200 ml (1 cup) of boiling water, cover with a lid and insist 15 minutes,periodically pressing on the bag with a spoon, then squeeze them.

    Before use, the infusion is shaken.

    Also externally in the form of fresh juice.

    Inside the prepared infusion take 1 / 2-1 / 3 cup 2-3 times a day.

    Side effects:

    When ingestion: nausea, vomiting.

    For external use: local skin irritation.

    Overdose:

    Cases of overdose with external application are not described. In case of an overdose, if ingested, paralysis of the respiratory center is possible.

    Treatment is symptomatic.

    Interaction:

    Not described.

    Special instructions:

    Can be used as part of monotherapy and combination therapy.

    When contact occurs, the dyeing of the skin.

    The plant is poisonous and should not be used without medical supervision.

    Contact with eyes may cause severe irritation (including cases of contact with the eyes of fingers with spots from contact with plant juice), with skin covering causes staining of different intensity.

    Instructions
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