Ecofucin - instructions for use, dose, side effects, contraindications

active substance: natamycin (in terms of 100% substance) - 100 mg; Excipients: lactulose - 300 mg, macrogol glyceryl hydroxy stearate - 200 mg, silicon dioxide colloid - 20 mg, fat solid (Suppocir AM) up to 2300 mg.

Description:

Suppositories torpedo shaped from light yellow to light brown in color. On the longitudinal section there should be no foreign inclusions. An air rod or a funnel-shaped depression is allowed.

Pharmacotherapeutic group:Antifungal agent

ATX: & nbsp

G.01.A.A.02 Natamycin

Pharmacodynamics:

Natamycin is an antifungal polyene antibiotic from the macrolide group, which has a wide spectrum of action. It has a fungicidal effect. It binds to sterols of cell membranes, violating their integrity and function, which leads to the death of microorganisms.

It is active against most pathogenic yeast-like fungi (especially Candida albicans), yeast (Torulopsis and Rhodotorula), as well as other pathogenic fungi (Aspergillus, Penicillium.). Less active against dermatophytes (Trichophyton, Microsporum, Epidermophyton). Does not affect in vitro on Gram-positive and Gram-negative bacteria.

Resistance to natamycin in clinical practice is not found.

Pharmacokinetics:Ecofucin® does not have a systemic effect, since it is practically not absorbed through intact skin and intact mucous membranes.

Indications:

Vaginitis, vulvitis, vulvovaginitis caused by fungi of the genus Candida.

Contraindications:Hypersensitivity to the components of the drug.

Carefully:not described

Pregnancy and lactation:It is possible to use the preparation Ecofucin® in pregnant women and during lactation.

Dosing and Administration:

With candidal vaginitis, vulvitis, vulvovaginitis: intravaginally one suppository for 3-6 days.

Suppositories, after being released from the contour pack, are inserted into the vagina while lying down, as deep as possible once a day for the night. The duration of the course of treatment is set individually. After the disappearance of the symptoms of the disease is recommended to continue treatment a few more days.During menstruation, the use of suppositories is interrupted.

With persistent flow of vaginitis caused by Candida albicans, additionally appointed natamycin in the form of tablets for oral administration: 1 tablet 4 times a day for 10-20 days for sanation of the focus of candidiasis infection in the intestine.

Side effects:With topical application, slight irritation and a burning sensation at the injection site are possible.

Overdose:At present, no cases of an overdose of Ecofucin® have been reported.

Interaction:Drug interaction of the drug Ecofucin® with other medicinal products is not described.

Special instructions:

With vaginal application under the influence of body temperature, suppositories turn into a foamy mass, which contributes to the uniform distribution of natamycin over the mucous membrane of the vagina.

During the period of treatment, there is no need to exclude sexual contact, but it is recommended to conduct a survey of sexual partners and, in case of candidal lesions, to treat with natamycin. In the period of treatment, barrier methods of contraception should be used.

Effect on the ability to drive transp. cf. and fur:The use of Ecofucin® does not affect the ability to drive vehicles and mechanisms.

Form release / dosage:

Vaginal suppositories 100 mg.

Packaging:

By 3 or 6 suppositories in a contour mesh package made of PVC / PE.

For 1 or 2 contour packs with 3 suppositories, or 1 contour pack of six suppositories, together with instructions for use in a pack of cardboard.

Storage conditions:

In a place protected from moisture and light at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-002341

Date of registration:13.01.2014

The owner of the registration certificate:AVVA RUS, OJSC AVVA RUS, OJSC Russia

Manufacturer: & nbsp

FARMEA France

Representation: & nbspAVVA ENG JSC AVVA ENG JSC Russia

Information update date: & nbsp24.06.2014

Illustrated instructions

Instructions

Ecofucin® (Ecofucin®)