Allergic reactions: urticaria, angioedema, erythema,skin eruptions, malignant exudative erythema (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), anaphylaxis, arthralgia, arthritis, eosinophilia, fever.
From the nervous system: dizziness, weakness, headache, agitation, hallucinations, convulsions, confusion.
From the genitourinary and urinary system: vaginitis, vaginal discharge, genital candidamycosis, genital and anus itching, interstitial nephritis, renal dysfunction, toxic nephropathy, increased creatinine, urea nitrogen.
From the digestive system: pain in the abdomen, dryness of the oral mucosa, anorexia, nausea, vomiting, dyspepsia, diarrhea, toxic hepatitis, cholestatic jaundice, hyperbilirubinemia, candidamycosis of the intestine, oral cavity, rarely pseudomembranous colitis.
On the part of the organs of hematopoiesis: neutropenia, thrombocytopenia, leukopenia, hemolytic anemia, aplastic anemia, pancytopenia, agranulocytosis, neutropenia, leukopenia, thrombocytopenia, bleeding. Laboratory indicators: increased activity of "liver" transaminases and alkaline phosphatase, an increase in prothrombin time.