Elkar - instructions for use, doses, side effects, contraindications

L-carnitine - a natural substance related to the vitamins of the group AT. Participates in metabolic processes as a carrier of long-chain fatty acids (palmitic, etc.) from the cytoplasm in the mitochondria,where these acids are subjected to the β-oxidation process with the formation of adenosine triphosphoric acid and acetyl-CoA. It improves protein and fat metabolism, increases secretion and enzymatic activity of gastric and intestinal juices, improves digestion, reduces excess body weight and reduces fat content in muscles. Increases resistance to physical stress, inhibits the formation of keto acids and anaerobic glycolysis, reduces the degree of lactic acidosis, promotes the economical consumption of glycogen and increases its stores in the liver and muscles.

Has an anabolic and lipolytic effect. Normalizes the increased basal metabolism in hyperthyroidism: it is a peripheral (indirect) antagonist of the action of thyroid hormones, and not a direct inhibitor of thyroid function.

Improves metabolism and energy supply of tissues.

Pharmacokinetics:

Well absorbed in the intestine, the concentration in the blood plasma reaches a maximum after 3 hours and remains in the therapeutic range for 9 hours. Easily penetrates into the liver, myocardium, more slowly - into the muscles. It is excreted by the kidneys, mainly in the form of acyl esters.

Indications:

The drug is used as part of complex therapy.

- a syndrome of anorexia nervosa;

- In the rehabilitation period after the transferred diseases and surgical interventions;

- intensive physical activities, sports training (to improve performance, endurance, reduce fatigue);

- complex therapy of chronic gastritis and chronic pancreatitis with a decreased secretory function;

- complex therapy of skin diseases (psoriasis, seborrheic eczema, focal scleroderma and discoid lupus erythematosus);

- hyperthyroidism of mild degree;

- complex therapy of neurological manifestations in vascular, toxic and traumatic brain lesions;

- diseases accompanied by a deficiency of carnitine or its increased loss (including myopathies, cardiomyopathies, mitochondrial diseases, hereditary diseases with concomitant mitochondrial insufficiency) - to compensate for its deficiency in the complex therapy;

- in pediatric practice (treatment of children under 3 years under the supervision of a doctor): when nursing preterm infants, newborns who have suffered a trauma or asphyxia; Children with sluggish sucking reflex and low weight gain; reduced muscle tone,with insufficient development of motor and mental functions, as well as for the purpose of preventing these disorders in children at risk; with growth retardation and lack of body weight in children and adolescents under 16 years.

Contraindications:Individual intolerance.

Pregnancy and lactation:

The use in pregnancy is contraindicated, due to the lack of research. It is necessary to stop breastfeeding during the period of application of the drug.

Dosing and Administration:

The drug is used as part of complex therapy.

Inside 30 minutes before meals, additionally diluted with liquid.

With anorexia nervosa, as well as during rehabilitation after the transferred diseases and surgical interventions: 2 g (2 scoops or 10 ml) 2 times a day for 1-2 months.

With prolonged physical loads: for 1-2 g (1-2 scoops or 5-10 ml) 2-3 times a day.

In complex therapy chronic gastritis and chronic pancreatitis with a decreased secretory function: 0.5 g (1/2 measuring spoon or 2.5 ml) 2 times a day, for 1-1.5 months.

For the treatment of skin diseases: 1 g (1 measuring spoon or 5 ml) 2 times a day for 2-4 weeks.

For hyperthyroidism of mild degree: for 0.25 g (25 drops) 2-3 times a day.The course of treatment is 20 days. The course of treatment is repeated after 1-2 months break or appointed for 3 months without interruption.

In vascular, toxic and traumatic lesions brain: for 0.5-1 g (1 / 2-1 scoop or 2.5-5 ml) per day for 3-5 days. If necessary, after 12-14 days, appoint a second course.

With diseases, accompanied by a deficiency of carnitine (primary and secondary carnitine insufficiency): up to 50-100 mg / kg (5-10 drops / kg) of body weight with a frequency of reception 2-3 times a day for 3-4 months.

Children are prescribed as an additive to sweet dishes (jelly, compote, juices). For children up to 3 years, the dose is determined by the attending physician, from 3 to 6 years - in a single dose of 0.1 g (10 drops) 2-3 times a day, at a daily dose of 0.2-0.3 g (20-30 drops). The course of treatment - 1 month.

Children from 6 to 12 years are prescribed in a single dose of 0.2-0.3 g (20-30 drops) 2-3 times a day, at a daily dose of 0.4-0.9 g (40-90 drops). The course of treatment - at least 1 month.

If the growth is delayed: 0.25 g (25 drops) 2-3 times a day. The course of treatment is 20 days. The course of treatment is repeated after 1 -2 months break or appointed for 3 months without interruption.

Side effects:Possible allergic reactions, gastralgia, dyspepsia, myasthenia gravis (in patients with uremia).

Overdose:

Symptoms: dyspeptic disorders, myasthenic disorders (in patients with uremia).

Treatment: gastric lavage, reception of activated charcoal.

Interaction:

Glucocorticosteroids contribute to the accumulation of the drug in tissues (except the liver), other anabolics enhance the effect.

Special instructions:Treatment of children under the age of 3 years is carried out under the supervision of a doctor.

Effect on the ability to drive transp. cf. and fur:

The drug does not affect the performance of potentially hazardous activities requiring special attention and quick reactions (driving and other vehicles, working with moving mechanisms, the work of a dispatcher and operator, etc.)

Form release / dosage:

Solution for ingestion 200 mg / ml.

Packaging:

100 ml glass bottle. To 100 ml in bottles of dark glass, Corked with lids with a control ring of the first opening. A measuring cup with a volume of 20 ml is put on the bottle. Each bottle, together with the instructions for use, is placed in a pack of cardboard.

50 ml glass bottle. To 50 ml in bottles of dark glass, sealed with caps with a control ring of the first opening. Each bottle, along with a measuring spoon with a nominal volume of 5 ml with risks labeled "1/4" and "1/2" (corresponding to 1.25 ml and 2.5 ml), is placed in a pack of cardboard with instructions for use.

25 ml glass bottle. To 25 ml in bottles of dark glass, ukuporennye lids with droppers, with a control ring of the first opening. Each bottle, together with the instructions for use, is placed in a pack of cardboard.

Storage conditions:

In a place protected from light and inaccessible to children at a temperature of 15 to 25 ° C. After opening - in the refrigerator for 2 months.

Shelf life:

3 years. Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LS-000184

Date of registration:17.03.2010

The owner of the registration certificate:PIK-PHARMA, LLC PIK-PHARMA, LLC Russia

Manufacturer: & nbsp

PIC-PHARMA PRO, LLC Russia

Corporation OLIFEN, CJSC Russia

Information update date: & nbsp13.10.2015

Illustrated instructions

Instructions

Elkar® (Elcar®)