Carnitine - instructions for use, dose, side effects, contraindications

Levokarnitin - a remedy for the correction of metabolic processes. This is a natural substance related to vitamins of group B.Participates in metabolic processes as a carrier of fatty acids through cell membranes from the cytoplasm to the mitochondria, where these acids undergo oxidation with the formation of a large amount of energy (in the form of ATP). It normalizes protein and fat metabolism, restores alkaline blood reserves, inhibits the formation of keto acids and anaerobic glycolysis, reduces the degree of lactic acidosis, and also increases motor activity and increases the tolerance of exercise, while contributing to the economical consumption of glycogen and its increase in stocks at liver.

Indications:

Secondary deficiency of carnitine. Disturbance of metabolism in the myocardium against a background of acute myocardial infarction, a state of hypoperfusion due to cardiogenic shock.

Contraindications:

Hypersensitivity to the components of the drug.

Carefully:

In patients with diabetes mellitus.

Pregnancy and lactation:The drug can be used during pregnancy and breastfeeding.

Dosing and Administration:

Secondary deficiency in hemodialysis: 2 g (2 ampoules) per day intravenously slowly after a hemodialysis session.

Acute myocardial infarction: the daily recommended dose is 100-200 mg (1 to 2 ml of the drug) per kg of body weight, 4 slow intravenous injections, or continuous intravenous administration during the first 48 hours, followed by a dose reduction of half the time until the end of the patient's stay in the cardiac compartment. Then go to oral use of 2 to 6 g (20 to 60 ml of the drug) or 2 to 6 tablets per day, as prescribed by the doctor, depending on the severity of the pathology.

In cardiogenic shock, intravenous administration should be continued until the patient leaves this condition.

Side effects:

Allergic reactions. Muscle weakness in patients suffering from uremia. With the rapid administration of the drug (80 cap / min and more), pain can occur along the veins that pass with a decrease in the rate of administration.

If any undesirable effect is not described in the instructions for use, it is necessary to contact your doctor in time.

Overdose:Toxic manifestations due to an overdose of levocarnitine have not been established.

Interaction:Glucocorticosteroids contribute to the accumulation of the drug in the tissues.

Special instructions:

The administration of levocarnitine to patients suffering from diabetes mellitus and receiving insulin or other oral hypoglycemic agents may lead to the development of hypoglycemia due to improved glucose uptake. Therefore, these patients should monitor the blood glucose level for timely correction of the dose of hypoglycemic drugs.

Intravenous administration should be slow (2-3 minutes).

There are no cases of habituation or metabolic dependence.

Form release / dosage:

Solution for intravenous administration 1g / 5 ml.

Packaging:

5 ml per ampoule of dark light-protective glass, 5 ampoules per tray of PVC, 1 pallet in a cardboard box with instructions for use

Storage conditions:

Store at a temperature not higher than 25 ° C, out of the reach of children.

Shelf life:

4 years. Do not use after expiry date.

Terms of leave from pharmacies:On prescription

Registration number:П N011461 / 03

Date of registration:18.03.2008

Expiration Date:Unlimited

The owner of the registration certificate:Sigma-Tau United Pharmaceutical Industries SpASigma-Tau United Pharmaceutical Industries SpA Italy

Manufacturer: & nbsp

SIGMA-TAU Industrie Farmaceutiche Riunite, S.p.A. Italy

Representation: & nbspPharma Riace Co., Ltd. Pharma Riace Co., Ltd. United Kingdom

Information update date: & nbsp14.12.2017

Illustrated instructions

Instructions

Carnithen (Carnitene)