Floxal - instructions for use, dose, side effects, contraindications

Active substance:
Ofloxacin	3,000 mg
Excipients
Benzalkonium chloride	0.025 mg
Sodium chloride	9,000 mg
1 M solution of hydrochloric acid	4,500-5,500 mg
1 M sodium hydroxide solution	2,500-3,500 mg
Water for injections	984.675-986.675mg up to 1 ml

Description:

Eye drops: Clear solution of light yellow color.

Pharmacotherapeutic group:Antimicrobial agent, fluoroquinolone.

ATX: & nbsp

Pharmacodynamics:

Ofloxacin is an antimicrobial drug from the group of fluoroquinolones of a wide spectrum of action.The bactericidal effect of ofloxacin is associated with the blockade of the DNA-gyrase enzyme in bacterial cells. Highly active against most gram-negative microorganisms: Esherichia coli, Salmonella spp., Proteus spp, Morganella morganii, Shigella spp., Klebsiella spp.,Enterobacter spp , Serratia spp, Citrobacter spp, Yersinia spp, Providencia spp, Haemopilus influenzae , Neisseria gonorrhoeae, Neisseria menigitidis, Mycoplasma spp, Legionella pneumophila, Acinetobacter spp, Chlamydia spp.

It is active against some strains of Gram-positive microorganisms, in particular Staphylococcus spp., Streptococcus spp.

Moderately sensitive to ofloxacin Enterococcus faecalis, Streptococcus pneumoniae, Pseudomonas spp.

Ofloxacin acts on microorganisms that produce beta-lactamase.

The drug is not sensitive to anaerobic bacteria (except B. Urealiticus).

Pharmacokinetics:

With local administration, the therapeutic concentration of the drug is achieved in the tissues of the eye.

Indications:

Infectious-inflammatory diseases of the anterior part of the eye caused by microorganisms sensitive to ofloxacin, blepharitis, barley, conjunctivitis, dacryocystitis, keratitis, corneal ulcers, chlamydial infection of the eyes, prevention and treatment of bacterial infection after eye injuries and surgical interventions.

Contraindications:

Hypersensitivity to the components of the drug, pregnancy, lactation.

Pregnancy and lactation:

There is no information on the harmful effect of ofloxacin on the fetus, but it is not recommended to use the drug during pregnancy and lactation.

Dosing and Administration:

The drug is instilled 1 drop into the conjunctival sac of the diseased eye 2-4 times a day. It is not recommended to use the drug for more than 2 weeks.

With simultaneous use of more than one preparation, a minimum 5-minute interval between instillations should be observed.

Side effects:

Allergic reactions; transient hyperemia of the conjunctiva, burning sensation, discomfort in the eyes, itching and dryness of the conjunctiva, photophobia, lacrimation, rarely - dizziness.

Interaction:

Drug interaction of the drug is not described.

Special instructions:

It is not recommended to wear contact lenses during the application of the drug. It is necessary to wear sunglasses (because of the possible development of photophobia) and avoid prolonged exposure to bright light.

Form release / dosage:Eye Drops 0,3%.

Packaging:

0.3% eye drops in 5 ml vials in a cardboard pack together with instructions for medical use.

Storage conditions:

Protected from light, at a temperature not exceeding 25 ° C and out of reach of children.

Shelf life:

3 years.After opening the vial or tube, use no more than 6 weeks.

Do not use after the expiry date printed on the package!

Terms of leave from pharmacies:On prescription

Registration number:П N015920 / 02

Date of registration:16.11.2009 / 26.11.2014

The owner of the registration certificate:VALEANT, LLC VALEANT, LLC Russia

Manufacturer: & nbsp

Dr. GERHARD MANN Chem.-Pharm. Fabrik, GmbH Germany

Information update date: & nbsp08.02.2018

Illustrated instructions

Instructions

Floxal® (Floxal)