From the digestive system: gastralgia, anorexia, nausea, vomiting, diarrhea, flatulence, abdominal pain, increased activity of "liver" transaminases, hyperbilirubinemia, cholestatic jaundice, pseudomembranous enterocolitis.
From the nervous system: headache, dizziness, motion uncertainty, tremor, convulsions, numbness and paresthesia of the limbs, intense dreams, nightmarish dreams, psychotic reactions, anxiety, psychomotor excitation, phobia, depression, confusion, hallucinations, increased intracranial pressure.
From the musculoskeletal system: tendonitis, myalgia, arthralgia, tendosynovitis, tendon rupture.
From the sense organs: violation of color perception, diplopia, violation of taste, smell, hearing and balance.
From the cardiovascular system: tachycardia, lowering blood pressure (with / in the introduction, with a sharp decrease in blood pressure, the introduction is discontinued), vasculitis, collapse.
Allergic reactions, skin rash, itchy skin, hives, allergic pneumonitis, allergic nephritis, eosinophilia, fever, Quincke's edema, bronchospasm, Stevens-Johnson and Lyell syndrome, photosensitivity, multiforme exudative erythema, anaphylactic shock.
From the skin: point hemorrhages (petechiae), dermatitis bullous hemorrhagic, papular rash with a cortex, indicating the defeat of blood vessels (vasculitis).
From the hematopoiesis: leukopenia, agranulocytosis, anemia, thrombocytopenia, pancytopenia, hemolytic and aplastic anemia.
From the urinary system: acute interstitial nephritis,
impaired renal function, hypercreatininaemia, increased urea levels.
Other: dysbacteriosis, superinfection, hypoglycemia (in patients with diabetes mellitus), vaginitis.
Local Reactions: pain, redness at the injection site, thrombophlebitis (with iv introduction).