From the digestive system: gastralgia, decreased appetite, nausea, vomiting, diarrhea, constipation, flatulence, abdominal pain, increased activity of "liver" transaminases, hyperbilirubinemia, cholestatic jaundice, pseudomembranous colitis, dryness of oral mucosa, pharyngitis.
From the nervous systemheadache, dizziness, impaired coordination of movements, tremor, convulsions, numbness and paresthesia of the extremities, intense dreams, nightmarish dreams, psychotic reactions, anxiety, state of arousal, phobias, depression, confusion, hallucinations, increased intracranial pressure, insomnia, nervousness.
From the side of the musculoskeletal system: tendonitis, myalgia, arthralgia, tendosinovitis, tendon rupture, pain in the extremities.
From the sense organs: violation of color perception, diplopia, violation of taste, smell, hearing and balance.
From the side of the cardiovascular system: tachycardia, increase or decrease in blood pressure.
Allergic reactions: skin rash, itching, urticaria, allergic pneumonitis, allergic nephritis, eosinophilia, fever, angioedema, bronchospasm, multiforme exudative erythema (including Stevens-Johnson syndrome) and toxic epidermal necrolysis (Lyell's syndrome), photosensitivity, vasculitis, anaphylactic shock, itching of the external genitalia in women.
From the skin: pinpoint hemorrhages (petechiae), bullous hemorrhagic dermatitis, papular rash with cortex, indicative of vascular lesions (vasculitis).
On the part of the organs of hematopoiesis: leukopenia, agranulocytosis, anemia (including hemolytic and aplastic), thrombocytopenia, pancytopenia.
From the urinary system: acute interstitial nephritis, impaired renal function, hypercreatininaemia, increased urea, dysuria, urinary retention.
Other: intestinal dysbacteriosis, superinfection, hypoglycemia (in patients with diabetes mellitus), vaginitis, chest pain, fatigue, asthenia, general weakness, vaginal discharge, epistaxis, thirst, weight loss.