Gentamicin is a bactericidal broad-spectrum antibiotic from the group of aminoglycosides. It binds to the 30S subunit of ribosomes and disrupts the protein synthesis, preventing the formation of a complex of transport and information RNA, with erroneous reading of the genetic code and the formation of non-functional proteins; polyribosomes split and lose the ability to synthesize protein (bacteriostasis).
Highly effective against gram-negative aerobic bacteria: Escherichia coli, Shigella spp., Klebsiella spp., Serratia spp., Proteus spp., Pseudomonas aeruginosa, Acinetobacter spp. The drug is also active against Gram-positive aerobic cocci: Staphylococcus spp. (including those that are resistant to penicillin). The drug is resistant to: Neisseria meningitidis, Treponema pallidum, some strains of Streptococcus spp., Anaerobic microorganisms.