Bactericidal broad-spectrum antibiotic from the group of aminoglycosides. It binds to the 30S subunit of the ribosomes and disrupts protein synthesis, preventing the formation of a complex of transport and information RNA, with erroneous reading of the genetic code and the formation of non-functional proteins; polyribosomes split and lose the ability to synthesize protein (bacteriostasis). Unlike other antibiotics, aminoglycosides have a bactericidal action - they reduce the barrier functions of cell membranes at high concentrations and cause the death of microorganisms.
Effective against Staphylococcus spp.(coagulase-positive and coagulase-negative), Pseudomonas aeruginosa, Proteus spp. (including indolpositive and indolotricative strains), Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, Haemophilus aegyptius, Enterobacter aerogenes, Moraxella lacunata, Neisseria spp. (including Neisseria gonorrhoeae).