Active substanceBenzalkonium chlorideBenzalkonium chloride
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  • Dosage form: & nbsp

    vaginal tablets

    Composition:
    1 tablet of vaginal contains:
    Active substance
    Benzalkonium chloride 20 mg
    Excipients
    Lactose anhydrous (lactopress) - 363 mg
    Cellulose microcrystalline - 344 mg
    Plasdon ES-630 (copovidone) 8 mg
    Polyplasdone IKS EL-10 (crospovidone) 32 mg
    Polyethylene glycol 4000 (macrogol) 21 mg
    Aerosil (silicon dioxide colloidal) - 4 mg
    Magnesium stearate - 8 mg
    Description:

    Tablets in the form of a ring of white or almost white color.

    Pharmacotherapeutic group:Contraceptive for topical use
    ATX: & nbsp

    D.08.A.J.01   Benzalkonium chloride

    G.02.B.B   Intravaginal contraceptives

    Pharmacodynamics:
    Contraceptive local (spermicidal) remedy, also has antiseptic antifungal, antiprotozoal effect; inactivates the virus Herpes simplex.

    It shows bactericidal activity against staphylococci, streptococci, gram-negative bacteria (intestinal and pseudomonas aeruginosa, gonococcus, proteus, Klebsiella and others), anaerobic bacteria, fungi and molds. It acts on strains of bacteria resistant to antibiotics and other chemotherapeutic drugs; suppresses plasmacoagulase and hyaluronidase of staphylococci.

    Spermicidal action is due to the ability to damage the membrane of spermatozoa (at the beginning of the flagella, then the head), which makes it impossible to fertilize the damaged sperm.The effect develops 5 minutes after the introduction of the vaginal tablet.

    It is active in the prevention of sexually transmitted diseases (gonorrhea, chlamydia, trichomoniasis). Does not affect the normal microflora of the vagina (including the Doderylein wand) and the hormonal cycle.

    Pharmacokinetics:Benzalkonium chloride practically not absorbed by the mucous membrane of the vagina, it is absorbed only on the surface of the walls of the vagina. It is excreted with normal physiological excretions or is removed by simple washing with water.
    Indications:

    Local contraception for women of reproductive age (with contraindications to the use of oral contraceptives or intrauterine contraception, postpartum period, lactation period, post-abortion period, premenopausal period, need for occasional protection from pregnancy, missing or late receipt of continuously used oral contraceptives) .

    It is possible to use together with the vaginal diaphragm or intrauterine contraceptive, as an additional local contraception, especially when using non-steroidal anti-inflammatory drugs.

    Contraindications:Hypersensitivity to the components of the drug, colpitis, ulceration and irritation of the mucous membrane of the vagina and uterus.
    Pregnancy and lactation:Harmful effect on the course of pregnancy does not have. It is not excreted in breast milk, it can be used during lactation.
    Dosing and Administration:
    Preliminarily releasing the tablet from the contour pack, insert it deep into the vagina, in the supine position for 5 minutes before sexual intercourse; durability actions - 4 hours

    Single dose: 1 tablet is designed for 1 sexual act. It is mandatory to introduce a new vaginal tablet in case of repeated sexual acts. The frequency of use is limited by the individual tolerability of the active substance and the frequency of sexual acts.

    Side effects:

    Allergic reactions (burning, itching), contact dermatitis.

    Interaction:

    Any drug administered intravaginally can reduce local spermicidal action (including soap and solutions, its containing). Iodine solutions (including 0.1% iodonate solution) inactivate the drug.

    Special instructions:

    Precautions for use

    To increase the efficiency, careful compliance with the method of application of the preparation is necessary.After coition is not recommended intravaginal use of hygiene (douching with soapy water, because soap destroys the active ; substance of the drug) to avoid loss of contraceptive effect; you can use the external toilet of the genital organs with clean water.

    Form release / dosage:

    Vaginal tablets 20 mg.

    Packaging:

    6 or 10 tablets per contour cell package.

    12 tablets per tube polymer.

    Each tube or 1 circuit cell pack of 10 tablets, or 2 contour packs of 6 tablets together with instructions for use in a pack of cardboard.

    Storage conditions:

    List B. At a temperature not higher than 25 ° C, in a dry place, protected from light and inaccessible to children.

    Shelf life:

    2 years.

    Do not use after the expiration date indicated on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LS-002186
    Date of registration:23.12.2011 / 02.10.2015
    Expiration Date:Unlimited
    The owner of the registration certificate:VEROPHARM SA VEROPHARM SA Russia
    Manufacturer: & nbsp
    Information update date: & nbsp16.04.2017
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