Glucosamine - instructions for use, dose, side effects, contraindications

Excipients (core): cellulose microcrystalline - 320.0 mg, silicon colloidal dioxide - 10.0 mg, croscarmellose sodium - 44.9 mg, water purified - 20.0 mg, povidone - K25 - 49.0 mg, magnesium stearate - 14.0 mg.

Auxiliary substances (shell): hypromellose - 22.8 mg, macrogol-4000 - 5.6 mg, titanium dioxide -11.6 mg.

Description:

Oval biconvex tablets with a risk on one side, covered with a film shell of white or almost white color.On the fracture are visible two layers - the core from white to white with a yellowish or brown tint of color and a film sheath.

Pharmacotherapeutic group:Reparation of tissue stimulant

ATX: & nbsp

M.01.A.X.05 Glucosamine

Pharmacodynamics:

Glucosamine helps to prevent cartilage destruction processes, stimulates the restoration of cartilaginous tissue, has anti-inflammatory and analgesic effect, normalizes the production of intra-articular fluid. Improves mobility joints, reduces the need for non-steroidal anti-inflammatory drugs (NSAIDs).

Pharmacokinetics:

Absorption in the gastrointestinal tract is 90%, bioavailability is 25%, half-life is 70 hours.

Indications:

Osteoarthritis of peripheral joints and spine, osteochondrosis.

Contraindications:

Hypersensitivity to the active ingredient and other components of the drug, severe chronic renal failure. It is not recommended to administer the drug during pregnancy and breastfeeding, as well as in childhood (up to 12 years) because of the lack of scientific clinical data in this category of patients.

Carefully:

Bronchial asthma, diabetes, intolerance to seafood (shrimp, shellfish).

Pregnancy and lactation:

Contraindicated use of the drug during pregnancy and breastfeeding because of the lack of scientific clinical data in this category of patients.

Dosing and Administration:

Inside. Adults and children over 12 years of age take 1 tablet 2 times a day, preferably while eating, with a glass of water. The symptomatic effect occurs 2-3 weeks after the application of the drug. The minimum course of therapy is 4-6 weeks. If necessary, the course of treatment is repeated at intervals of 2 months.

Duration and treatment scheme is appointed by the attending physician.

Side effects:

Violation of the function of the gastrointestinal tract (pain in epigastrium, flatulence, diarrhea, constipation, nausea), skin allergic reactions (urticaria, skin itch, erythema), from the nervous system (headache, drowsiness).

Overdose:

Symptoms: cases of overdose are unknown. Treatment: gastric lavage, symptomatic therapy.

Interaction:

Increases the absorption of tetracyclines, reduces the effect of semisynthetic penicillins, chloramphenicol.Strengthens the effect of coumarin anticoagulants. The drug is compatible with paracetamol, NSAIDs and glucocorticosteroids. When combined with NSAIDs, it increases the anti-inflammatory and analgesic effect of the latter.

Special instructions:

It is not recommended to take children under 12 years of age due to a lack of scientific data for this category of patients. The risk of allergic reactions increases with intolerance to seafood. When using the drug in patients with impaired glucose tolerance, with severe hepatic and renal insufficiency, medical control is necessary.

Effect on the ability to drive transp. cf. and fur:

The influence of glucosamine on the ability to drive a car and control mechanisms has not been investigated. However, based on the pharmacodynamic properties and general safety profile, it seems unlikely that glucosamine has such an impact.

Form release / dosage:

Film-coated tablets 750 mg.

Packaging:

For 10 tablets in a contour mesh box made of polyvinylchloride film and aluminum foil printed lacquered.

10, 20, 30, 40, 50, 60 or 100 tablets in cans of polyethylene terephthalate or polypropylene for drugs sealed with high-pressure polyethylene caps with a first opening control or polypropylene caps with a "push-turn" system or with low-density polyethylene caps pressure with the control of the first opening.

One jar or 1, 2, 3, 4, 5, 6 or 10 contour squares, together with the instructions for use, are placed in a cardboard package (bundle).

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-004619

Date of registration:26.12.2017

Expiration Date:26.12.2022

The owner of the registration certificate:ATOLL, LLC ATOLL, LLC Russia

Manufacturer: & nbsp

OZONE, LLC Russia

Information update date: & nbsp24.01.2018

Illustrated instructions

Instructions

Glucosamine (Glucosamine)