Sustilac - instructions for use, dose, side effects, contraindications

Excipients: calcium hydrogen phosphate 62 mg, hypromellose (K200M) 40 mg, povidone K90 40 mg, microcrystalline cellulose 83 mg, hypromellose 80 mg, silicon colloid 5 mg, Shell composition: hypromellose E-5 - 20 mg, macrogol-6000 - 6 mg, opadrai white (titanium dioxide, macrogol, hypromellose) - 11 mg.

Description:

Oval tablets of white or almost white color, covered with a film membrane.

Pharmacotherapeutic group:Reparation of tissue stimulant

ATX: & nbsp

M.01.A.X.05 Glucosamine

Pharmacodynamics:

Glucosamine helps to prevent cartilage destruction processes, stimulates the restoration of cartilaginous tissue, has anti-inflammatory and analgesic effect, normalizes the production of intra-articular fluid. Improves mobility of joints, reduces the need for non-steroidal anti-inflammatory drugs (NSAIDs).

Pharmacokinetics:

After oral administration, it is rapidly and completely absorbed in the gastrointestinal tract; the prolonged form provides a continuous release of the active substance and its uniform absorption; the bioavailability of glucosamine after oral administration is 25-26% (the effect of "primary transmission" through the liver). After distribution in tissues, the highest concentrations are observed in the liver, kidneys and cartilaginous tissue. Metabolized to water, carbon dioxide and urea. It is excreted mainly by the kidneys.

Indications:

Osteoarthritis of peripheral joints and spine.

Contraindications:

Hypersensitivity to glucosamine and other components of the drug, severe renal dysfunction, pregnancy, lactation, age under 18 years (efficacy and safety not established).

Carefully:

Bronchial asthma, diabetes, intolerance to seafood (shrimp, shellfish).

Dosing and Administration:

Inside. Take 1 tablet 1 time per day, the tablet is swallowed whole, squeezed with water, for 6-12 weeks.

On the recommendation of the doctor, the treatment course is repeated at intervals of 2 months. Steady therapeutic effect is achieved with taking the drug for 6 months.

Side effects:

Tolerability of the drug is good, in some cases, possible: violations of the gastrointestinal tract (pain in epigastrium, flatulence, constipation or diarrhea, nausea, skin allergic reactions (urticaria, skin itching).

Overdose:

Symptoms: cases of overdose are unknown.

Treatment: gastric lavage, symptomatic therapy.

Interaction:

Increases the absorption of tetracyclines, reduces the effect of semisynthetic penicillins, chloramphenicol. The drug is compatible with paracetamol, NSAIDs and glucocorticosteroids. When combined with NSAIDs, it increases the anti-inflammatory and analgesic effect of the latter.

Special instructions:

The risk of allergic reactions increases with intolerance to seafood.

Effect on the ability to drive transp. cf. and fur:

There are no restrictions on the management of vehicles and complex mechanisms during the period of application of the drug.

Form release / dosage:Modified-release tablets coated with a film sheath 1500 mg.

Packaging:

For 15 tablets in a contour mesh box made of PVC film and aluminum foil. 4 contour squares with instructions for use in cardboard pack.

Storage conditions:

In a dry, protected from light place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years. Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-001838

Date of registration:14.09.2012

The owner of the registration certificate:REMEDIYA, LLC REMEDIYA, LLC Russia

Manufacturer: & nbsp

MEDREICH, Ltd. India

Information update date: & nbsp19.11.2015

Illustrated instructions

Instructions

Sustilac (Sustilak)