Active substanceGlucosamineGlucosamine
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  • Dosage form: & nbspPowder for solution for oral administration
    Composition:

    Composition per package (4 grams):

    Active substance: glucosamine sodium sulfate chloride - 1884.0 mg, in terms of glucosamine sulfate - 1500.0 mg.

    Excipients: sorbitol - 2081.0 mg, citric acid monohydrate - 25.0 mg, macrogol-4000 - 10.0 mg.

    Description:White or white with yellowish powdered granulated powder.
    Pharmacotherapeutic group:Reparation of tissue stimulant
    ATX: & nbsp

    M.01.A.X.05   Glucosamine

    Pharmacodynamics:

    Anti-inflammatory drug, replenishes the endogenous deficiency of glucosamine, increases the permeability of the joint capsule, restores enzymatic processes in the cells of the synovial membrane and articular cartilage.It promotes the fixation of sulfur during the synthesis of chondroitinsulfuric acid, facilitates the normal deposition of calcium in the bone tissue, inhibits the development of degenerative processes in the joints, restores their function, reducing joint pain.

    Pharmacokinetics:

    Absorption in the gastrointestinal tract is 90%, bioavailability is 25%, half-life is 70 hours.

    Indications:

    Osteoarthritis of peripheral joints and spine, osteochondrosis.

    Contraindications:

    Individual hypersensitivity to the active substance and other components of the drug, severe chronic renal failure. It is not recommended to administer the drug during pregnancy and lactation, and also in childhood (up to 12 years) because of the lack of scientific clinical data in this category of patients. Intolerance to fructose.

    Carefully:

    Bronchial asthma, diabetes, intolerance to seafood (shrimp, shellfish).

    Pregnancy and lactation:

    It is not recommended to use the drug during pregnancy and lactation due to the lack of scientific clinical data in this category of patients.

    Dosing and Administration:

    Adults and children from 12 years.

    Inside.The contents of one packet are dissolved in 200 ml of water, taken once a day for 6-12 pedel. The symptomatic effect occurs 2-3 weeks after the application of the drug. The minimum course of therapy is 4-6 weeks.

    If necessary, the course of treatment is repeated at intervals of 2 months.

    Duration and treatment scheme is appointed by the attending physician.

    Side effects:

    Disturbance of the function of the gastrointestinal tract (pain in epigastrium, flatulence, diarrhea, constipation, nausea), skin allergic reactions (urticaria, skin itch, erythema), from the nervous system (headache, drowsiness).

    Overdose:

    Symptoms: cases of overdose are unknown. Treatment: gastric lavage, symptomatic therapy.

    Interaction:

    Increases the absorption of tetracyclines, reduces the effect of semisynthetic penicillins, chloramphenicol. Strengthens the effect of coumarin anticoagulants. The drug is compatible with paracetamol, non-steroidal anti-inflammatory drugs (HPBP) and glucocorticosteroids. When combined with NSAIDs, it increases the anti-inflammatory and analgesic effect of the latter.

    Special instructions:

    It is not recommended to take children under 12 years of age due to a lack of scientific data for this category of patients. The risk of allergic reactions increases with intolerance to seafood. When using the drug in patients with impaired glucose tolerance, with severe hepatic and renal insufficiency, medical control is necessary.

    Effect on the ability to drive transp. cf. and fur:

    None.

    Form release / dosage:

    Powder to prepare a solution for oral administration of 1500 mg.

    Packaging:

    By 4 g of powder in heat-sealed bags.

    For 10, 20, 30, 40, 50 or 100 bags, together with the instructions for use, are placed in a cardboard package (bundle).

    4 grams of powder in cans of polyethylene terephthalate.

    One bank along with the instruction for use is placed in a cardboard package (bundle).

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years. Do not use the drug after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-003199
    Date of registration:16.09.2015
    Expiration Date:16.09.2020
    The owner of the registration certificate:ATOLL, LLC ATOLL, LLC Russia
    Manufacturer: & nbsp
    Representation: & nbspOZONE LLC OZONE LLC Russia
    Information update date: & nbsp22.04.2017
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