Glutargin is a compound of arginine and glutamic acid, which play an important role in providing biochemical processes of neutralization and excretion of the highly toxic metabolite of nitrogen metabolism - ammonia.Hypoammonemic effects of the drug are realized by activating the neutralization of ammonia in the ornithine cycle of urea synthesis, the binding of ammonia to non-toxic glutamine, as well as increasing the excretion of ammonia from the central nervous system and its excretion from the body. As a result, general toxic, including neurotoxic, effects of ammonia are reduced.
Glutargin has a hepatoprotective effect, possessing antioxidant, antihypoxic and membrane-stabilizing activity, positively affects the energy supply in hepatocytes. With alcohol intoxication, Glutargin stimulates the utilization of alcohol in the monooxygenase system of the liver, prevents the inhibition of the key enzyme for the utilization of ethanol - alcohol dehydrogenase; accelerates inactivation and elimination of toxic products of ethanol metabolism as a result of increased formation and oxidation of succinic acid; reduces the inhibitory effect of alcohol on the CNS due to the neurotransmitter properties of the excitatory glutamic acid. Glutargin has no embryotoxic, gonadotoxic and mutagenic effects, does not cause allergic and immunotoxic reactions.