Immunoglobulin is injected intramuscularly into the upper outer quadrant of the gluteus muscle or the external surface of the thigh. Do not administer the drug intravenously.
Before the injection, the ampoule with the drug is kept for 2 hours at room temperature (20 + 2) ° C. To prevent the formation of foam, the drug is drawn into the syringe with a needle with a wide lumen.
The drug in the opened ampoule is not subject to storage.
The dose of the drug and the frequency of its administration depend on the indications for use.
Prevention of hepatitis A
The drug is administered once in doses: children from 1 to 6 years - 0.75 ml; up to 10 years - 1.5 ml; older than 10 years and adults - 3 ml. Repeated administration of immunoglobulin in case of need of prophylaxis of hepatitis A is shown not earlier than in 2 months.
Prevention of measles
The drug is administered once from 3 months of age not with measles and not vaccinated against infection no later than 6 days after contact with the patient. The dose of the drug to children (1.5 or 3.0 ml) is determined depending on the health status and the time elapsed since the contact.
Adults, and also children in contact with mixed infections, the drug is administered in a dose of 3.0 ml.
Prevention and treatment of influenza
The drug is administered once in doses: children under 2 years of age -1.5 ml; from 2 to 7 years - 3.0 ml; older than 7 years and adults - 4,5-6,0 ml. In the treatment of severe forms of influenza, repeated (24-48 hours) administration of immunoglobulin at the same dose is indicated.
Prophylaxis of pertussis
The drug is administered two times at intervals of 24 hours in a single dose of 3.0 ml to children who have not had pertussis, at the earliest possible time of contact with the patient.
Prevention of meningococcal infection
The drug is administered once in doses to children aged 6 months to 7 years, no later than 7 days after contact with the patient with a generalized form of meningococcal infection in doses of 1.5 ml for children under 3 years and 3.0 ml for children over 3 years old.
Prevention of poliomyelitis
The drug is administered once in doses of 3.0-6.0 ml of an unvaccinated or inferiorly grafted poliomyelitis vaccine to children at the earliest possible time after contact with the patient with a paralytic form of poliomyelitis.
Treatment of hypo- and agamoglobulinemia
The drug is administered at a dose of 1.0 per kg of body weight; The calculated dose can be entered into 2-3 doses at intervals of 24 hours. The subsequent administration of immunoglobulin is carried out according to the indications no earlier than one month later.
Increase of resistance of the organism during the reconvalescence of acute infectious diseases with prolonged course and with chronic and protracted pneumonia.
The drug is administered in a single dose of 0.15-0.2 ml per 1 kg of body weight. Multiplicity of administration (up to 4 injections) is determined by the doctor; intervals between injections are 2-3 days.